Taar5 MGI Mouse Gene Detail - MGI:2685073 - trace amine-associated receptor 5

Symbol

Taar5
Name

trace amine-associated receptor 5
Synonyms

LOC215854

Feature Type

protein coding gene
IDs

MGI:2685073
NCBI Gene: 215854
Alliance

gene page

Sequence Map

Chr10:23846604-23847617 bp, + strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 10, 11.40 cM
Mapping Data

1 experiment

SNPs within 2kb

112 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2685073	protein coding gene	Chr10:23846604-23847617 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0017080	protein coding gene	Chr10:21906780-21907793 (+)
A/J	MGP_AJ_G0017058	protein coding gene	Chr10:21263287-21264300 (+)
AKR/J	MGP_AKRJ_G0017020	protein coding gene	Chr10:21609046-21610059 (+)
BALB/cJ	MGP_BALBcJ_G0017020	protein coding gene	Chr10:21341756-21342769 (+)
C3H/HeJ	MGP_C3HHeJ_G0016840	protein coding gene	Chr10:21816521-21817534 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0017478	protein coding gene	Chr10:22562066-22563079 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0015179	protein coding gene	Chr10:19992152-19993165 (+)
CAST/EiJ	MGP_CASTEiJ_G0016421	protein coding gene	Chr10:21711941-21712954 (+)
CBA/J	MGP_CBAJ_G0016813	protein coding gene	Chr10:23559161-23560174 (+)
DBA/2J	MGP_DBA2J_G0016919	protein coding gene	Chr10:21005499-21006512 (+)
FVB/NJ	MGP_FVBNJ_G0016915	protein coding gene	Chr10:20718481-20719494 (+)
LP/J	MGP_LPJ_G0016995	protein coding gene	Chr10:21890967-21891980 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0016945	protein coding gene	Chr10:23697721-23698734 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0017513	protein coding gene	Chr10:21476554-21477567 (+)
PWK/PhJ	MGP_PWKPhJ_G0016206	protein coding gene	Chr10:20741649-20742662 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0015988	protein coding gene	Chr10:21293911-21294924 (+)
WSB/EiJ	MGP_WSBEiJ_G0016484	protein coding gene	Chr10:21577543-21578556 (+)

Human Ortholog

TAAR5, trace amine associated receptor 5

Vertebrate Orthologs

7

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

TAAR5, trace amine associated receptor 5
Synonyms

PNR, taR-5
Links

HGNC:30236

NCBI Gene ID: 9038

neXtProt AC: NX_O14804

UniProt: O14804
Chr Location

6q23.2; chr6:132588592-132616747 (-) GRCh38

MGI Vertebrate Homology

Taar5 stringent orthology
1 human;1 mouse;1 rat;5 zebrafish
HCOP

vertebrate homology predictions: TAAR5
Gene Tree

Taar5

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Phenotype Summary

1 phenotype from 1 allele in 1 genetic background
22 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

11
Chemically induced (other)

1
Endonuclease-mediated

1
Targeted

9
Genomic Mutations

4 involving Taar5
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

24 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

Mice homozygous for a knock-out allele exhibit abnormal olfactory system physiology.

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All GO Annotations

18
GO References

11

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

726
Tissues

6
cDNA Data

5
Literature Summary

2

Images

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

Allen Institute

GEO

Expression Atlas

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All Sequences

29
RefSeq

2
UniProt

2
CCDS

CCDS23738.1

Ensembl

ENSMUSG00000069706 (Evidence)
NCBI Gene

215854

			Length	Strain/Species	Flank
genomic	215854	NCBI Gene Model \| MGI Sequence Detail	1014	C57BL/6J	± kb
transcript	NM_001009574	RefSeq \| MGI Sequence Detail	1014	C57BL/6
polypeptide	Q5QD14	UniProt \| EBI \| MGI Sequence Detail	337	Not Applicable

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UniProt

2 Sequences
Protein Ontology

PR:000001679 trace amine-associated receptor 5

(term hierarchy)
InterPro Domains

IPR017981 GPCR, family 2-like, 7TM

IPR017452 GPCR, rhodopsin-like, 7TM

IPR000276 G protein-coupled receptor, rhodopsin-like

IPR050569 Trace Amine-Associated Receptor

IPR009132 Trace amine associated receptor family
GlyGen

Q5QD14 1 site

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All nucleic 7

cDNA 5

Primer pair 1

Other 1

Microarray probesets 1

Summaries

All 45

Developmental Gene Expression 2

Gene Ontology 11

Phenotypes 22
Earliest

J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
Latest

J:352390 Guo L, et al., Structural basis of amine odorant perception by a mammal olfactory receptor. Nature. 2023 Jun;618(7963):193-200

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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