Ism2 MGI Mouse Gene Detail - MGI:2685110

Sequence Map

Chr12:87325412-87346479 bp, - strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2685110	protein coding gene	Chr12:87325412-87346624 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0019985	protein coding gene	Chr12:88178339-88202991 (-)
A/J	MGP_AJ_G0019943	protein coding gene	Chr12:84829880-84851700 (-)
AKR/J	MGP_AKRJ_G0019918	protein coding gene	Chr12:87135521-87158460 (-)
BALB/cJ	MGP_BALBcJ_G0019922	protein coding gene	Chr12:85162629-85183450 (-)
C3H/HeJ	MGP_C3HHeJ_G0019728	protein coding gene	Chr12:87623563-87646567 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0020374	protein coding gene	Chr12:90720721-90745427 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0017992	protein coding gene	Chr12:81709217-81731176 (-)
CAST/EiJ	MGP_CASTEiJ_G0019278	protein coding gene	Chr12:82653831-82678959 (-)
CBA/J	MGP_CBAJ_G0019700	protein coding gene	Chr12:94192149-94213113 (-)
DBA/2J	MGP_DBA2J_G0019813	protein coding gene	Chr12:84325123-84346568 (-)
FVB/NJ	MGP_FVBNJ_G0019800	protein coding gene	Chr12:83319199-83340930 (-)
LP/J	MGP_LPJ_G0019887	protein coding gene	Chr12:88059263-88080227 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0019839	protein coding gene	Chr12:96955926-96980234 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0020406	protein coding gene	Chr12:86760675-86781722 (-)
PWK/PhJ	MGP_PWKPhJ_G0019042	protein coding gene	Chr12:78879304-78903437 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0018837	protein coding gene	Chr12:81265982-81293890 (-)
WSB/EiJ	MGP_WSBEiJ_G0019331	protein coding gene	Chr12:87538320-87559270 (-)

Vertebrate Orthology Source

Alliance of Genome Resources

MGI Vertebrate Homology

Ism2 stringent orthology
1 human;1 mouse;1 rat;2 zebrafish
HCOP

vertebrate homology predictions: ISM2
Gene Tree

Ism2

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Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.

Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.

Cellular Component

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

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			Length	Strain/Species	Flank
genomic	ENSMUSG00000050671	Ensembl Gene Model \| MGI Sequence Detail	21068	C57BL/6J	± kb
transcript	ENSMUST00000125733	Ensembl \| MGI Sequence Detail	2526	Not Applicable
polypeptide	ENSMUSP00000117108	Ensembl \| MGI Sequence Detail	493	Not Applicable

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Summaries

All 22

Developmental Gene Expression 1

Phenotypes 9
Earliest

J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
Latest

J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24