Fam81b MGI Mouse Gene Detail - MGI:2685122 - family with sequence similarity 81, member B

Fam81b Gene Detail

Symbol

Fam81b
Name

family with sequence similarity 81, member B
Synonyms

LOC238726

Feature Type

protein coding gene
IDs

MGI:2685122
NCBI Gene: 238726
Alliance

gene page
Transcription Start Sites

5 TSS

Sequence Map

Chr13:76349827-76427034 bp, - strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 13, 40.96 cM
Mapping Data

1 experiment

SNPs within 2kb

2132 from dbSNP Build 142
Strain Annotations

1

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2685122	protein coding gene	Chr13:76349827-76453191 (-)
129S1/SvImJ	no annotation
A/J	no annotation
AKR/J	no annotation
BALB/cJ	no annotation
C3H/HeJ	no annotation
C57BL/6NJ	no annotation
CAROLI/EiJ	no annotation
CAST/EiJ	no annotation
CBA/J	no annotation
DBA/2J	no annotation
FVB/NJ	no annotation
LP/J	no annotation
NOD/ShiLtJ	no annotation
NZO/HlLtJ	no annotation
PWK/PhJ	no annotation
SPRET/EiJ	no annotation
WSB/EiJ	no annotation

Human Ortholog

FAM81B, family with sequence similarity 81 member B

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

FAM81B, family with sequence similarity 81 member B
Links

HGNC:26335

NCBI Gene ID: 153643

neXtProt AC: NX_Q96LP2

UniProt: Q96LP2
Chr Location

5q15; chr5:95391366-95450454 (+) GRCh38

MGI Vertebrate Homology

Fam81b stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: FAM81B
Gene Tree

Fam81b

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Phenotype Summary

4 phenotypes from 1 allele in 1 genetic background
7 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

3
Chemically induced (other)

1
Endonuclease-mediated

2
Genomic Mutations

1 involving Fam81b
Find Mice (IMSR)

9 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

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Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.

Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.

Cellular Component

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

731
Tissues

2
cDNA Data

4
Literature Summary

1

Images

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase fam81b

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All Sequences

15
RefSeq

5
UniProt

1

Ensembl

ENSMUSG00000109228 (Evidence)
NCBI Gene

238726

			Length	Strain/Species	Flank
genomic	238726	NCBI Gene Model \| MGI Sequence Detail	77208	C57BL/6J	± kb
transcript	NM_001370926	RefSeq \| MGI Sequence Detail	1734	C57BL/6
polypeptide	NP_001357855	RefSeq \| MGI Sequence Detail	412	C57BL/6

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UniProt

1 Sequence
InterPro Domains

IPR029619 Protein FAM81

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All nucleic 4

cDNA 4

Microarray probesets 3

Summaries

All 21

Developmental Gene Expression 1

Phenotypes 7
Earliest

J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
Latest

J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for Fam81b:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr123270	Chr13:76420057-76420072 (-)	6,969 bp
Tssr123269	Chr13:76420025-76420032 (-)	7,005 bp
Tssr123268	Chr13:76419439-76419477 (-)	7,576 bp
Tssr123267	Chr13:76419434-76419438 (-)	7,598 bp
Tssr123266	Chr13:76404657-76404692 (-)	22,359 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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