Gm525 MGI Mouse Gene Detail - MGI:2685371

Symbol

Gm525
Name

predicted gene 525
Synonyms

LOC217071

Feature Type

protein coding gene
IDs

MGI:2685371
NCBI Gene: 217071
Alliance

gene page
Transcription Start Sites

4 TSS

Sequence Map

Chr11:88964667-88983866 bp, + strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 11, 54.34 cM
Mapping Data

1 experiment

SNPs within 2kb

263 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2685371	protein coding gene	Chr11:88957346-88983890 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0018931	protein coding gene	Chr11:90841556-90861906 (+)
A/J	MGP_AJ_G0018899	protein coding gene	Chr11:87300332-87317998 (+)
AKR/J	MGP_AKRJ_G0018869	protein coding gene	Chr11:89977178-89995651 (+)
BALB/cJ	MGP_BALBcJ_G0018872	protein coding gene	Chr11:87721882-87741241 (+)
C3H/HeJ	MGP_C3HHeJ_G0018686	protein coding gene	Chr11:90000703-90018040 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0019324	protein coding gene	Chr11:93640098-93659347 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0016955	protein coding gene	Chr11:84327486-84345220 (+)
CAST/EiJ	MGP_CASTEiJ_G0018241	protein coding gene	Chr11:90705872-90730118 (+)
CBA/J	MGP_CBAJ_G0018657	protein coding gene	Chr11:97617255-97641656 (+)
DBA/2J	MGP_DBA2J_G0018765	protein coding gene	Chr11:86848568-86868544 (+)
FVB/NJ	MGP_FVBNJ_G0018754	protein coding gene	Chr11:86352671-86369299 (+)
LP/J	MGP_LPJ_G0018835	protein coding gene	Chr11:91366004-91382764 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0018781	protein coding gene	Chr11:97516421-97535390 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0019364	protein coding gene	Chr11:90180938-90198833 (+)
PWK/PhJ	MGP_PWKPhJ_G0018011	protein coding gene	Chr11:87715177-87732317 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0017801	protein coding gene	Chr11:89768592-89784621 (+)
WSB/EiJ	MGP_WSBEiJ_G0018290	protein coding gene	Chr11:90074656-90093437 (+)

Human Ortholog

C17orf67, chromosome 17 open reading frame 67

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

C17orf67, chromosome 17 open reading frame 67
Links

HGNC:27900

NCBI Gene ID: 339210

neXtProt AC: NX_Q0P5P2

UniProt: Q0P5P2
Chr Location

17q22; chr17:56791913-56838773 (-) GRCh38

MGI Vertebrate Homology

Gm525 stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: C17orf67
Gene Tree

Gm525

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References

1 with disease annotations

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Phenotype Summary

15 phenotype references

All Mutations and Alleles

33
Chemically induced (other)

1
Endonuclease-mediated

2
Gene trapped

25
Targeted

5
Genomic Mutations

4 involving Gm525
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

11 strains or lines available

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All GO Annotations

1
GO References

1

Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.

Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

706
cDNA Data

8

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas

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All Sequences

33
RefSeq

4
UniProt

2
CCDS

CCDS36279.1

Ensembl

ENSMUSG00000072553 (Evidence)
NCBI Gene

217071

			Length	Strain/Species	Flank
genomic	ENSMUSG00000072553	Ensembl Gene Model \| MGI Sequence Detail	19200	C57BL/6J	± kb
transcript	ENSMUST00000100619	Ensembl \| MGI Sequence Detail	557	Not Applicable
polypeptide	ENSMUSP00000098184	Ensembl \| MGI Sequence Detail	90	Not Applicable

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UniProt

2 Sequences
Protein Ontology

PR:000059771 uncharacterized protein C17orf67

(term hierarchy)
InterPro Domains

IPR027870 Protein of unknown function DUF4543

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All nucleic 8

cDNA 8

Microarray probesets 1

Summaries

All 31

Diseases 1

Gene Ontology 1

Phenotypes 15
Earliest

J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
Latest

J:174216 Terzian T, et al., Rpl27a mutation in the sooty foot ataxia mouse phenocopies high p53 mouse models. J Pathol. 2011 Aug;224(4):540-52

TSS for Gm525:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr104087	Chr11:88964747-88964760 (+)	87 bp
Tssr3637	Chr11:88969033-88969037 (+)	4,368 bp
Tssr104088	Chr11:88983108-88983119 (+)	18,447 bp
Tssr104089	Chr11:88983125-88983142 (+)	18,467 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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