Gfy MGI Mouse Gene Detail - MGI:2685427 - golgi-associated olfactory signaling regulator

Symbol

Gfy
Name

golgi-associated olfactory signaling regulator
Synonyms

Gm581, Goofy

Feature Type

protein coding gene
IDs

MGI:2685427
NCBI Gene: 100039953
Alliance

gene page
Transcription Start Sites

1 TSS

Sequence Map

Chr7:44825773-44828993 bp, - strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 7, Syntenic
Mapping Data

1 experiment

SNPs within 2kb

126 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2685427	protein coding gene	Chr7:44825773-44829021 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0032206	protein coding gene	Chr7:45413060-45416310 (-)
A/J	MGP_AJ_G0032185	protein coding gene	Chr7:44551170-44554409 (-)
AKR/J	MGP_AKRJ_G0032121	protein coding gene	Chr7:45781643-45784891 (-)
BALB/cJ	MGP_BALBcJ_G0032197	protein coding gene	Chr7:44550307-44553814 (-)
C3H/HeJ	MGP_C3HHeJ_G0031913	protein coding gene	Chr7:46274844-46278079 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0032689	protein coding gene	Chr7:47683803-47688462 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0029703	protein coding gene	Chr7:47113189-47116426 (-)
CAST/EiJ	MGP_CASTEiJ_G0031241	protein coding gene	Chr7:37666565-37669811 (-)
CBA/J	MGP_CBAJ_G0031877	protein coding gene	Chr7:49244100-49249751 (-)
DBA/2J	MGP_DBA2J_G0032035	protein coding gene	Chr7:44223398-44226903 (-)
FVB/NJ	MGP_FVBNJ_G0031986	protein coding gene	Chr7:43998397-44001994 (-)
LP/J	MGP_LPJ_G0032113	protein coding gene	Chr7:46096833-46100091 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0032023	protein coding gene	Chr7:47960837-47963957 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0032705	protein coding gene	Chr7:44996971-45000027 (-)
PWK/PhJ	MGP_PWKPhJ_G0030964	protein coding gene	Chr7:37589534-37592840 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0030801	protein coding gene	Chr7:33009641-33014191 (-)
WSB/EiJ	MGP_WSBEiJ_G0031358	protein coding gene	Chr7:45491773-45496261 (-)

Human Ortholog

GFY, golgi associated olfactory signaling regulator

Vertebrate Orthologs

2

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

GFY, golgi associated olfactory signaling regulator
Synonyms

Goofy
Links

HGNC:44663

NCBI Gene ID: 100507003

neXtProt AC: NX_I3L273

UniProt: I3L273
Chr Location

chr19:49423747-49428987 (+) GRCh38

MGI Vertebrate Homology

Gfy stringent orthology
1 human;1 mouse;1 rat
HCOP

vertebrate homology predictions: GFY
Gene Tree

Gfy

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Phenotype Summary

4 phenotypes from 1 allele in 1 genetic background
2 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

2
Endonuclease-mediated

1
Targeted

1
Find Mice (IMSR)

23 strains or lines available
Comparison Matrix

Gene Expression + Phenotype
Recombinase Activity

Comparison Matrix Gene Expression + Recombinase Activity

Mice homozygous for a null mutation display short olfactory epithelium (OE) cilia, reduced odorant induced local field potentials in the OE and impaired olfaction.

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All GO Annotations

5
GO References

1

Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

920
Tissues

21
cDNA Data

5
Literature Summary

2

Images

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

GEO

Expression Atlas

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All Sequences

32
RefSeq

2
UniProt

2
CCDS

CCDS57548.1

Ensembl

ENSMUSG00000095276 (Evidence)
NCBI Gene

100039953

			Length	Strain/Species	Flank
genomic	ENSMUSG00000095276	Ensembl Gene Model \| MGI Sequence Detail	3221	C57BL/6J	± kb
transcript	ENSMUST00000179443	Ensembl \| MGI Sequence Detail	1849	Not Applicable
polypeptide	ENSMUSP00000135927	Ensembl \| MGI Sequence Detail	504	Not Applicable

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UniProt

2 Sequences
Protein Ontology

PR:000059742 Golgi-associated olfactory signaling regulator

(term hierarchy)
GlyGen

J3KML8 1 site

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All nucleic 5

cDNA 5

Summaries

All 14

Developmental Gene Expression 2

Gene Ontology 1

Phenotypes 2
Earliest

J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
Latest

J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;

TSS for Gfy:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr72333	Chr7:44828963-44828991 (-)	16 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24