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Zfp512b Gene Detail
Summary
  • Symbol
    Zfp512b
  • Name
    zinc finger protein 512B
  • Synonyms
    LOC269401, Znf512b
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685478
    NCBI Gene: 269401
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:181223925-181234572 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 103.67 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    165 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685478
 protein coding gene Chr2:181223896-181234596 (-)
129S1/SvImJ MGP_129S1SvImJ_G0027029
 protein coding gene Chr2:188193202-188204174 (-)
A/J MGP_AJ_G0026995
 protein coding gene Chr2:180433362-180444062 (-)
AKR/J MGP_AKRJ_G0026965
 protein coding gene Chr2:185847717-185858511 (-)
BALB/cJ MGP_BALBcJ_G0027003
 protein coding gene Chr2:180913844-180924550 (-)
C3H/HeJ MGP_C3HHeJ_G0026745
 protein coding gene Chr2:186196373-186207103 (-)
C57BL/6NJ MGP_C57BL6NJ_G0027449
 protein coding gene Chr2:193638543-193649234 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0024813
 protein coding gene Chr2:171117174-171128011 (-)
CAST/EiJ MGP_CASTEiJ_G0026204
 protein coding gene Chr2:184468267-184478962 (-)
CBA/J MGP_CBAJ_G0026722
 protein coding gene Chr2:200635525-200646228 (-)
DBA/2J MGP_DBA2J_G0026859
 protein coding gene Chr2:179535742-179546450 (-)
FVB/NJ MGP_FVBNJ_G0026825
 protein coding gene Chr2:178151791-178165821 (-)
LP/J MGP_LPJ_G0026961
 protein coding gene Chr2:188211384-188225882 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0026845
 protein coding gene Chr2:203200803-203212773 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0027509
 protein coding gene Chr2:185816018-185828767 (-)
PWK/PhJ MGP_PWKPhJ_G0025940
 protein coding gene Chr2:177061910-177072669 (-)
SPRET/EiJ MGP_SPRETEiJ_G0025740
 protein coding gene Chr2:182319383-182330042 (-)
WSB/EiJ MGP_WSBEiJ_G0026276
 protein coding gene Chr2:186802125-186812830 (-)



Homology
more
  • Human Ortholog
    ZNF512B, zinc finger protein 512B
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZNF512B, zinc finger protein 512B
  • Synonyms
    GM632
  • Links
    NCBI Gene ID: 57473
    neXtProt AC: NX_Q96KM6
    UniProt: Q96KM6

  • Chr Location
    20q13.33; chr20:63956704-63969930 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    4
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    725
  • Tissues
    1
  • cDNA Data
    6
  • Literature Summary
    1
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 269401 NCBI Gene Model | MGI Sequence Detail 10648 C57BL/6J ±  kb
transcript NM_001409726 RefSeq | MGI Sequence Detail 5776 C57BL/6  
polypeptide NP_001396655 RefSeq | MGI Sequence Detail 910 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    8 Sequences
  • InterPro Domains
    IPR052274 Krueppel-type C2H2 zinc-finger
    IPR048403 Zinc finger 512, zinc finger
    IPR036236 Zinc finger C2H2 superfamily
    IPR013087 Zinc finger C2H2-type
    IPR048408 Zinc finger protein 512, C2HC zinc finger
Molecular
Reagents
less
  • All nucleic 6
    cDNA 6

    Microarray probesets 2
References
more
  • Summaries
    All 21
    Developmental Gene Expression 1
    Gene Ontology 1
    Phenotypes 6
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory