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Pou2af3 Gene Detail
Summary
  • Symbol
    Pou2af3
  • Name
    POU class 2 homeobox associating factor 3
  • Synonyms
    Colca2, Gm684, LOC270157, OCA-T2
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685530
    NCBI Gene: 100502940
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:51181558-51189865 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 28.02 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    237 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685530
 protein coding gene Chr9:51181558-51190951 (-)
129S1/SvImJ MGP_129S1SvImJ_G0034799
 protein coding gene Chr9:50193930-50202211 (-)
A/J MGP_AJ_G0034780
 protein coding gene Chr9:48667168-48675469 (-)
AKR/J MGP_AKRJ_G0034708
 protein coding gene Chr9:49682080-49690376 (-)
BALB/cJ MGP_BALBcJ_G0034772
 protein coding gene Chr9:48417406-48425707 (-)
C3H/HeJ MGP_C3HHeJ_G0034482
 protein coding gene Chr9:50175235-50183536 (-)
C57BL/6NJ MGP_C57BL6NJ_G0035292
 protein coding gene Chr9:51602009-51610305 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032205
 protein coding gene Chr9:48128484-48136788 (-)
CAST/EiJ MGP_CASTEiJ_G0033804
 protein coding gene Chr9:50116281-50124627 (-)
CBA/J MGP_CBAJ_G0034454
 protein coding gene Chr9:53419140-53427140 (-)
DBA/2J MGP_DBA2J_G0034613
 protein coding gene Chr9:48523986-48532289 (-)
FVB/NJ MGP_FVBNJ_G0034554
 protein coding gene Chr9:47740587-47748888 (-)
LP/J MGP_LPJ_G0034694
 protein coding gene Chr9:50560505-50568784 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0034597
 protein coding gene Chr9:54995866-55004167 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0035313
 protein coding gene Chr9:49677600-49685924 (-)
PWK/PhJ MGP_PWKPhJ_G0033509
 protein coding gene Chr9:48505797-48514095 (-)
SPRET/EiJ MGP_SPRETEiJ_G0033344
 protein coding gene Chr9:49969022-49977348 (-)
WSB/EiJ MGP_WSBEiJ_G0033917
 protein coding gene Chr9:49680244-49688536 (-)



Homology
more
  • Human Ortholog
    POU2AF3, POU class 2 homeobox associating factor 3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    POU2AF3, POU class 2 homeobox associating factor 3
  • Synonyms
    C11orf93, CASC13, COLCA2, LOH11CR1G, OCA-T2
  • Links
    NCBI Gene ID: 120376
    neXtProt AC: NX_A8K830
    UniProt: A8K830

  • Chr Location
    11q23.1; chr11:111298546-111308735 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    14 phenotypes from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    4
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 100502940 NCBI Gene Model | MGI Sequence Detail 8308 C57BL/6J ±  kb
    transcript NM_001195681 RefSeq | MGI Sequence Detail 1274 C57BL/6  
    polypeptide F8VPY8 UniProt | EBI | MGI Sequence Detail 253 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      1 Sequence
    • InterPro Domains
      IPR047571 OCA domain
      IPR043265 POU class 2 homeobox associating factor 3
    Molecular
    Reagents
    less
    • All nucleic 4
      cDNA 4
    Other
    Accession IDs
    less
    MGI:5883135, MGI:7287399
    References
    more
    • Summaries
      All 24
      Gene Ontology 5
      Phenotypes 8
    • Earliest
      J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory