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Lrrc10b Gene Detail
Summary
  • Symbol
    Lrrc10b
  • Name
    leucine rich repeat containing 10B
  • Synonyms
    Gm705, LOC278795, SerdinR
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685551
    NCBI Gene: 278795
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:10432735-10434811 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 19, 6.60 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    119 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685551
 protein coding gene Chr19:10432735-10434837 (-)
129S1/SvImJ MGP_129S1SvImJ_G0024844
 protein coding gene Chr19:7792750-7794815 (-)
A/J MGP_AJ_G0024812
 protein coding gene Chr19:7264240-7266307 (-)
AKR/J MGP_AKRJ_G0024787
 protein coding gene Chr19:7547687-7552056 (-)
BALB/cJ MGP_BALBcJ_G0024812
 protein coding gene Chr19:7309359-7311420 (-)
C3H/HeJ MGP_C3HHeJ_G0024578
 protein coding gene Chr19:7439459-7441524 (-)
C57BL/6NJ MGP_C57BL6NJ_G0025260
 protein coding gene Chr19:8146720-8148795 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022687
 protein coding gene Chr19:7682332-7684415 (-)
CAST/EiJ MGP_CASTEiJ_G0024051
 protein coding gene Chr19:7095548-7097613 (-)
CBA/J MGP_CBAJ_G0024552
 protein coding gene Chr19:8187170-8189245 (-)
DBA/2J MGP_DBA2J_G0024679
 protein coding gene Chr19:7276647-7278710 (-)
FVB/NJ MGP_FVBNJ_G0024646
 protein coding gene Chr19:7318793-7320858 (-)
LP/J MGP_LPJ_G0024766
 protein coding gene Chr19:7761782-7763857 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0024673
 protein coding gene Chr19:8092295-8094350 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0025308
 protein coding gene Chr19:7568332-7570395 (-)
PWK/PhJ MGP_PWKPhJ_G0023796
 protein coding gene Chr19:6718429-6720583 (-)
SPRET/EiJ MGP_SPRETEiJ_G0023601
 protein coding gene Chr19:6751583-6754116 (-)
WSB/EiJ MGP_WSBEiJ_G0024113
 protein coding gene Chr19:7452540-7454608 (-)



Homology
more
  • Human Ortholog
    LRRC10B, leucine rich repeat containing 10B
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LRRC10B, leucine rich repeat containing 10B
  • Links
    NCBI Gene ID: 390205
    neXtProt AC: NX_A6NIK2
    UniProt: A6NIK2

  • Chr Location
    11q12.2; chr11:61508749-61511018 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype reference
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    721
  • Tissues
    8
  • cDNA Data
    3
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 278795 NCBI Gene Model | MGI Sequence Detail 2077 C57BL/6J ±  kb
transcript NM_001111140 RefSeq | MGI Sequence Detail 2077 C57BL/6  
polypeptide NP_001104610 RefSeq | MGI Sequence Detail 292 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR001611 Leucine-rich repeat
    IPR050216 Leucine-rich repeat domain-containing protein
    IPR032675 Leucine-rich repeat domain superfamily
    IPR003591 Leucine-rich repeat, typical subtype
Molecular
Reagents
less
  • All nucleic 5
    cDNA 3
    Primer pair 2

    Microarray probesets 1
References
more
  • Summaries
    All 15
    Developmental Gene Expression 2
    Gene Ontology 1
    Phenotypes 1
  • Earliest
    J:98394 Adameyko II, et al., Expression and regulation of mouse SERDIN1, a highly conserved cardiac-specific leucine-rich repeat protein. Dev Dyn. 2005 Jun;233(2):540-52
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory