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Mdfic2 Gene Detail
Summary
  • Symbol
    Mdfic2
  • Name
    MyoD family inhibitor domain containing 2
  • Synonyms
    Gm765, LOC330390
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685611
    NCBI Gene: 330390
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:98212669-98319715 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 45.67 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    2593 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685611
 protein coding gene Chr6:98212665-98319715 (-)
129S1/SvImJ MGP_129S1SvImJ_G0031079
 protein coding gene Chr6:100113610-100225390 (-)
A/J MGP_AJ_G0031048
 protein coding gene Chr6:96331028-96435433 (-)
AKR/J MGP_AKRJ_G0030979
 protein coding gene Chr6:98958238-99069303 (-)
BALB/cJ MGP_BALBcJ_G0031059
 protein coding gene Chr6:96281091-96392282 (-)
C3H/HeJ MGP_C3HHeJ_G0030649
 protein coding gene Chr6:85350334-85465768 (+)
C57BL/6NJ MGP_C57BL6NJ_G0031518
 protein coding gene Chr6:102643631-102760675 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0028682
 protein coding gene Chr6:94165867-94270734 (-)
CAST/EiJ MGP_CASTEiJ_G0030166
 protein coding gene Chr6:99169526-99283735 (-)
CBA/J MGP_CBAJ_G0030745
 protein coding gene Chr6:106535696-106659948 (-)
DBA/2J MGP_DBA2J_G0030898
 protein coding gene Chr6:95461136-95570125 (-)
FVB/NJ MGP_FVBNJ_G0030852
 protein coding gene Chr6:94633240-94741929 (-)
LP/J MGP_LPJ_G0030978
 protein coding gene Chr6:100155584-100271209 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0030886
 protein coding gene Chr6:110441434-110556313 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0031545
 protein coding gene Chr6:98849627-98958951 (-)
PWK/PhJ MGP_PWKPhJ_G0029882
 protein coding gene Chr6:94446963-94554562 (-)
SPRET/EiJ MGP_SPRETEiJ_G0029710
 protein coding gene Chr6:97754220-97872592 (-)
WSB/EiJ MGP_WSBEiJ_G0030250
 protein coding gene Chr6:99350850-99463525 (-)



Homology
more
  • Human Ortholog
    MDFIC2, MyoD family inhibitor domain containing 2
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MDFIC2, MyoD family inhibitor domain containing 2
  • Links
    NCBI Gene ID: 107986096
    UniProt: A0A1B0GVS7

  • Chr Location
    chr3:70194479-70312638 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000090667 Ensembl Gene Model | MGI Sequence Detail 107047 C57BL/6J ±  kb
transcript ENSMUST00000164491 Ensembl | MGI Sequence Detail 3132 Not Applicable  
polypeptide ENSMUSP00000127120 Ensembl | MGI Sequence Detail 189 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR026134 MyoD family inhibitor/MyoD family inhibitor domain-containing protein
Molecular
Reagents
less
  • All nucleic 4
    cDNA 4
Other
Accession IDs
less
MGI:6460394
References
more
  • Summaries
    All 16
    Gene Ontology 1
    Phenotypes 5
  • Earliest
    J:87486 Akeson EC, Chromosomal inversion discovered in C3H/HeJ mice. JAX Notes. 2003;491:15
  • Latest
    J:330636 Iwata S, et al., An efficient i-GONAD method for creating and maintaining lethal mutant mice using an inversion balancer identified from the C3H/HeJJcl strain. G3 (Bethesda). 2021;11(8)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory