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Lrrc37 Gene Detail
Summary
  • Symbol
    Lrrc37
  • Name
    leucine rich repeat containing 37
  • Synonyms
    Gm884, LOC380730
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685730
    NCBI Gene: 380730
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:103425403-103511966 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 67.38 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1955 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685730
 protein coding gene Chr11:103425403-103512309 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019264
 protein coding gene Chr11:106618292-106716192 (-)
A/J MGP_AJ_G0019232
 protein coding gene Chr11:102093329-102172346 (-)
AKR/J MGP_AKRJ_G0019201
 protein coding gene Chr11:105235574-105326147 (-)
BALB/cJ MGP_BALBcJ_G0019206
 protein coding gene Chr11:102536448-102615402 (-)
C3H/HeJ MGP_C3HHeJ_G0019015
 protein coding gene Chr11:105461008-105551672 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019656
 protein coding gene Chr11:109929447-110020831 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017281
 protein coding gene Chr11:99508193-99586867 (-)
CAST/EiJ MGP_CASTEiJ_G0018569
 protein coding gene Chr11:106478480-106560790 (-)
CBA/J MGP_CBAJ_G0018984
 protein coding gene Chr11:114495353-114589113 (-)
DBA/2J MGP_DBA2J_G0019096
 protein coding gene Chr11:101596352-101673453 (-)
FVB/NJ MGP_FVBNJ_G0019087
 protein coding gene Chr11:101121417-101196566 (-)
LP/J MGP_LPJ_G0019165
 protein coding gene Chr11:107117401-107201091 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019117
 protein coding gene Chr11:113837055-113931031 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019693
 protein coding gene Chr11:105622878-105704488 (-)
PWK/PhJ MGP_PWKPhJ_G0018333
 protein coding gene Chr11:102681992-102759634 (-)
SPRET/EiJ MGP_SPRETEiJ_G0018124
 protein coding gene Chr11:105366968-105445214 (-)
WSB/EiJ MGP_WSBEiJ_G0018618
 protein coding gene Chr11:105623466-105706608 (-)



Homology
more
  • Human Ortholog
    LRRC37A, leucine rich repeat containing 37A
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LRRC37A, leucine rich repeat containing 37A
  • Synonyms
    LRRC37, LRRC37A1
  • Links
    NCBI Gene ID: 9884
    neXtProt AC: NX_A6NMS7
    UniProt: A6NMS7

  • Chr Location
    17q21.31
  • Human Ortholog
    LRRC37A2, leucine rich repeat containing 37 member A2
  • Synonyms
    LRRC37
  • Links
    NCBI Gene ID: 474170
    neXtProt AC: NX_A6NM11
    UniProt: A6NM11

  • Chr Location
    chr17:46372792-47049128 (+)  GRCh38
  • Human Ortholog
    LRRC37A3, leucine rich repeat containing 37 member A3
  • Synonyms
    LRRC37, LRRC37A
  • Links
    NCBI Gene ID: 374819
    neXtProt AC: NX_O60309
    UniProt: O60309

  • Chr Location
    17q24.1; chr17:64854130-64919480 (-)  GRCh38
  • Human Ortholog
    LRRC37B, leucine rich repeat containing 37B
  • Synonyms
    LRRC37
  • Links
    NCBI Gene ID: 114659
    neXtProt AC: NX_Q96QE4
    UniProt: Q96QE4

  • Chr Location
    17q11.2
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000034239 Ensembl Gene Model | MGI Sequence Detail 86564 C57BL/6J ±  kb
transcript ENSMUST00000059279 Ensembl | MGI Sequence Detail 10977 Not Applicable  
polypeptide ENSMUSP00000058511 Ensembl | MGI Sequence Detail 3643 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • InterPro Domains
    IPR001611 Leucine-rich repeat
    IPR015753 Leucine-rich repeat-containing protein 37
    IPR032754 Leucine-rich repeat-containing protein 37, N-terminal
    IPR032675 Leucine-rich repeat domain superfamily
    IPR003591 Leucine-rich repeat, typical subtype
    IPR029423 LRRC37A/B like protein 1, C-terminal
  • GlyGen
    A2A9H6 4 sites, 4 N-linked glycans (4 sites)
Molecular
Reagents
less
  • All nucleic 2
    cDNA 2

    Microarray probesets 2
Other
Accession IDs
less
MGI:7468978
References
more
  • Summaries
    All 21
    Phenotypes 7
  • Earliest
    J:56548 Zheng B, et al., Engineering a mouse balancer chromosome. Nat Genet. 1999 Aug;22(4):375-8
  • Latest
    J:174216 Terzian T, et al., Rpl27a mutation in the sooty foot ataxia mouse phenocopies high p53 mouse models. J Pathol. 2011 Aug;224(4):540-52
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory