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Ap5b1 Gene Detail
Summary
  • Symbol
    Ap5b1
  • Name
    adaptor-related protein complex 5, beta 1 subunit
  • Synonyms
    Gm962
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685808
    NCBI Gene: 381201
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:5618053-5621289 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 19, 4.34 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    141 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685808
 protein coding gene Chr19:5610278-5621290 (+)
129S1/SvImJ MGP_129S1SvImJ_G0024716
 protein coding gene Chr19:2542314-2545501 (+)
A/J MGP_AJ_G0024682
 protein coding gene Chr19:2403604-2406791 (+)
AKR/J MGP_AKRJ_G0024655
 protein coding gene Chr19:2466297-2469484 (+)
BALB/cJ MGP_BALBcJ_G0024682
 protein coding gene Chr19:2399874-2403061 (+)
C3H/HeJ MGP_C3HHeJ_G0024450
 protein coding gene Chr19:2483429-2486616 (+)
C57BL/6NJ MGP_C57BL6NJ_G0025129
 protein coding gene Chr19:2597150-2600337 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022559
 protein coding gene Chr19:2305167-2308367 (+)
CAST/EiJ MGP_CASTEiJ_G0023922
 protein coding gene Chr19:2507659-2510846 (+)
CBA/J MGP_CBAJ_G0024422
 protein coding gene Chr19:2722134-2725321 (+)
DBA/2J MGP_DBA2J_G0024549
 protein coding gene Chr19:2400638-2403825 (+)
FVB/NJ MGP_FVBNJ_G0024515
 protein coding gene Chr19:2390233-2393420 (+)
LP/J MGP_LPJ_G0024635
 protein coding gene Chr19:2524267-2527454 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0024545
 protein coding gene Chr19:2565714-2568901 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0025177
 protein coding gene Chr19:2488626-2491813 (+)
PWK/PhJ MGP_PWKPhJ_G0023668
 protein coding gene Chr19:2423877-2427064 (+)
SPRET/EiJ MGP_SPRETEiJ_G0023473
 protein coding gene Chr19:2472620-2475792 (+)
WSB/EiJ MGP_WSBEiJ_G0023984
 protein coding gene Chr19:2497109-2500296 (+)



Homology
more
  • Human Ortholog
    AP5B1, adaptor related protein complex 5 subunit beta 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    AP5B1, adaptor related protein complex 5 subunit beta 1
  • Synonyms
    AP-5, PP1030
  • Links
    NCBI Gene ID: 91056
    neXtProt AC: NX_Q2VPB7
    UniProt: Q2VPB7

  • Chr Location
    11q13.1; chr11:65773898-65780976 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype reference
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    5
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    14
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000049562 Ensembl Gene Model | MGI Sequence Detail 3237 C57BL/6J ±  kb
transcript ENSMUST00000096318 Ensembl | MGI Sequence Detail 3092 Not Applicable  
polypeptide ENSMUSP00000094042 Ensembl | MGI Sequence Detail 876 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 14
    cDNA 14

    Microarray probesets 2
References
more
  • Summaries
    All 23
    Gene Ontology 5
    Phenotypes 1
  • Earliest
    J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
  • Latest
    J:320005 Hirst J, et al., The fifth adaptor protein complex. PLoS Biol. 2011 Oct;9(10):e1001170
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory