Cd101 MGI Mouse Gene Detail - MGI:2685862

Symbol

Cd101
Name

CD101 antigen
Synonyms

Igsf2, LOC381460

Feature Type

protein coding gene
IDs

MGI:2685862
NCBI Gene: 630146
Alliance

genome feature page
Transcription Start Sites

8 TSS

Sequence Map

Chr3:100900845-100936872 bp, - strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 3, 43.90 cM
Mapping Data

1 experiment

SNPs within 2kb

348 from dbSNP Build 142
Strain Annotations

19

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2685862	protein coding gene	Chr3:100899505-100936872 (-)
129S1/SvImJ	ENSMUSG00200043157	protein coding gene	Chr3:97505597-97541637 (-)
A/J	ENSMUSG00195041978	protein coding gene	Chr3:97911400-97947427 (-)
AKR/J	ENSMUSG00220038829	protein coding gene	Chr3:96271525-96307547 (-)
BALB/cJ	ENSMUSG00180031255	protein coding gene	Chr3:97851007-97887023 (-)
C3H/HeJ	ENSMUSG00175022779	protein coding gene	Chr3:97397253-97433277 (-)
C57BL/6NJ	ENSMUSG00215027278	protein coding gene	Chr3:98163063-98199100 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0025428	protein coding gene	Chr3:95112615-95152738 (-)
CAST/EiJ	ENSTCUG00005018208	protein coding gene	Chr3:98123113-98159600 (-)
CBA/J	ENSMUSG00210050705	protein coding gene	Chr3:98019441-98055462 (-)
DBA/2J	ENSMUSG00185041418	protein coding gene	Chr3:98505317-98541652 (-)
FVB/NJ	ENSMUSG00205017806	protein coding gene	Chr3:97082585-97118624 (-)
JF1/MsJ	ENSUMUG00000047185	protein coding gene	Chr3:97217016-97253109 (-)
LP/J	ENSMUSG00230041945	protein coding gene	Chr3:100434250-100470283 (-)
NOD/ShiLtJ	ENSMUSG00190028271	protein coding gene	Chr3:98692760-98729098 (-)
NZO/HlLtJ	ENSMUSG00225019560	protein coding gene	Chr3:102884444-102920485 (-)
PWK/PhJ	ENSLUMG00010028519	protein coding gene	Chr3:97307727-97343756 (-)
SPRET/EiJ	ENSMSPG00010045337	protein coding gene	Chr3:97555866-97592117 (-)
WSB/EiJ	ENSIUOG00005029747	protein coding gene	Chr3:98039084-98074460 (-)

Human Ortholog

CD101, CD101 molecule

Vertebrate Orthologs

2

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

CD101, CD101 molecule
Synonyms

EWI-101, IGSF2, V7
Links

HGNC:5949

NCBI Gene ID: 9398

UniProt: Q93033
Chr Location

1p13.1; chr1:117001721-117036552 (+) GRCh38

MGI Vertebrate Homology

Cd101 stringent orthology
1 human;1 mouse;1 rat
HCOP

vertebrate homology predictions: CD101
Gene Tree

Cd101

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References

1 with disease annotations

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Phenotype Summary

1 phenotype from 1 allele in 1 genetic background
10 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

8
Chemically induced (other)

1
Endonuclease-mediated

3
Gene trapped

2
Radiation induced

1
Targeted

1
Genomic Mutations

2 involving Cd101
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

46 strains or lines available

Mice homozygous for a knock-out allele exhibit reduced Gr-1+ cells.

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All GO Annotations

9
GO References

4

Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

597
cDNA Data

2

Tissue x Stage Matrix

Other Mouse Links

GEO

Expression Atlas

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All Sequences

35
RefSeq

5
UniProt

2
CCDS

CCDS51019.1, CCDS51020.1

Ensembl

ENSMUSG00000086564 (Evidence)
NCBI Gene

630146

			Length	Strain/Species	Flank
genomic	ENSMUSG00000086564	Ensembl Gene Model \| MGI Sequence Detail	36028	C57BL/6J	± kb
transcript	ENSMUST00000147399	Ensembl \| MGI Sequence Detail	3299	Not Applicable
polypeptide	ENSMUSP00000116643	Ensembl \| MGI Sequence Detail	1033	Not Applicable

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UniProt

2 Sequences
Protein Ontology

PR:000001089 immunoglobulin superfamily member 2

(term hierarchy)
InterPro Domains

IPR003599 Immunoglobulin domain subtype

IPR013151 Immunoglobulin-like beta-sandwich domain

IPR007110 Immunoglobulin-like domain

IPR036179 Immunoglobulin-like domain superfamily

IPR013783 Immunoglobulin-like fold

IPR003598 Immunoglobulin subtype 2

IPR051102 Immunoglobulin superfamily V-set and transmembrane domain-containing protein

IPR013106 Immunoglobulin V-set domain
GlyGen

A8E0Y8 2 sites

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All nucleic 2

cDNA 2

Microarray probesets 1

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MGI:2685580

Summaries

All 30

Diseases 1

Gene Ontology 4

Phenotypes 10
Earliest

J:70677 Cook SA, et al., Mouse paracentric inversion In(3)55Rk mutates the urate oxidase gene. Cytogenet Cell Genet. 2001;93(1-2):77-82
Latest

J:302829 Lu J, et al., Mouse models for human hyperuricaemia: a critical review. Nat Rev Rheumatol. 2019 Jul;15(7):413-426

TSS for Cd101:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr34768	Chr3:100936859-100936874 (-)	5 bp
Tssr34767	Chr3:100936840-100936849 (-)	27 bp
Tssr34766	Chr3:100919994-100920003 (-)	16,873 bp
Tssr34765	Chr3:100919464-100919478 (-)	17,401 bp
Tssr34764	Chr3:100919446-100919457 (-)	17,420 bp
Tssr34763	Chr3:100919427-100919444 (-)	17,436 bp
Tssr34762	Chr3:100911126-100911145 (-)	25,736 bp
Tssr34761	Chr3:100911070-100911105 (-)	25,784 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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