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Bclaf3 Gene Detail
Summary
  • Symbol
    Bclaf3
  • Name
    Bclaf1 and Thrap3 family member 3
  • Synonyms
    2310067E24Rik, A830080D01Rik, LOC382252
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685992
    NCBI Gene: 382252
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:158315639-158376077 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 73.55 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1176 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685992
 protein coding gene ChrX:158309684-158376077 (+)
129S1/SvImJ MGP_129S1SvImJ_G0036226
 protein coding gene ChrX:157428273-157498732 (+)
A/J MGP_AJ_G0036196
 protein coding gene ChrX:156708182-156775720 (+)
AKR/J MGP_AKRJ_G0036124
 protein coding gene ChrX:161694444-161758868 (+)
BALB/cJ MGP_BALBcJ_G0036189
 protein coding gene ChrX:154792124-154858462 (+)
C3H/HeJ MGP_C3HHeJ_G0035895
 protein coding gene ChrX:157825196-157895619 (+)
C57BL/6NJ MGP_C57BL6NJ_G0036711
 protein coding gene ChrX:162120675-162192347 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0033533
 protein coding gene ChrX:147972377-148039178 (+)
CAST/EiJ MGP_CASTEiJ_G0035184
 protein coding gene ChrX:136863702-136937140 (+)
CBA/J MGP_CBAJ_G0035870
 protein coding gene ChrX:166741017-166819392 (+)
DBA/2J MGP_DBA2J_G0036036
 protein coding gene ChrX:155694093-155760566 (+)
FVB/NJ MGP_FVBNJ_G0035967
 protein coding gene ChrX:154810097-154878758 (+)
LP/J MGP_LPJ_G0036121
 protein coding gene ChrX:158592777-158669390 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0035999
 protein coding gene ChrX:175423667-175503998 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0036752
 protein coding gene ChrX:156974706-157045787 (+)
PWK/PhJ MGP_PWKPhJ_G0034882
 protein coding gene ChrX:133740683-133809458 (+)
SPRET/EiJ MGP_SPRETEiJ_G0034703
 protein coding gene ChrX:137295278-137363138 (+)
WSB/EiJ MGP_WSBEiJ_G0035319
 protein coding gene ChrX:154940539-155011403 (+)



Homology
more
  • Human Ortholog
    BCLAF3, BCLAF1 and THRAP3 family member 3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    BCLAF3, BCLAF1 and THRAP3 family member 3
  • Synonyms
    CXorf23
  • Links
    NCBI Gene ID: 256643
    neXtProt AC: NX_A2AJT9
    UniProt: A2AJT9

  • Chr Location
    Xp22.12; chrX:19912860-19991061 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 2 alleles in 1 genetic background
    4 images
    14 phenotype references
  • All Mutations and Alleles
    79
  • Endonuclease-mediated
    2
  • Gene trapped
    73
  • Radiation induced
    1
  • Spontaneous
    1
  • Targeted
    2
  • Genomic Mutations
    2 involving Bclaf3
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    96 strains or lines available
Male chimeras hemizygous for either of two different gene trapped alleles of this gene appear normal at E8.5.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    5
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    735
  • Tissues
    29
  • cDNA Data
    46
  • Literature Summary
    1
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 382252 NCBI Gene Model | MGI Sequence Detail 60439 C57BL/6J ±  kb
transcript NR_152562 RefSeq | MGI Sequence Detail 4215 C57BL/6  
polypeptide A2AG58 UniProt | EBI | MGI Sequence Detail 752 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 48
    Genomic 2
    cDNA 46

    Microarray probesets 5
Other
Accession IDs
less
MGI:1916899, MGI:5906013
References
more
  • Summaries
    All 38
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 14
  • Earliest
    J:46359 Blair HJ, et al., Mouse mutants carrying deletions that remove the genes mutated in Coffin-Lowry syndrome and lactic acidosis. Hum Mol Genet. 1998 Mar;7(3):549-55
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory