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Rhox12 Gene Detail
Summary
  • Symbol
    Rhox12
  • Name
    reproductive homeobox 12
  • Synonyms
    LOC382282
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685994
    NCBI Gene: 382282
  • Member of
    Rhox cluster
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:37192954-37199784 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome X, 22.36 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    260 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685994
protein coding gene ChrX:37192939-37199784 (-)
129S1/SvImJ MGP_129S1SvImJ_G0035660
protein coding gene ChrX:33043782-33050920 (-)
A/J MGP_AJ_G0035644
protein coding gene ChrX:33109743-33116311 (-)
AKR/J MGP_AKRJ_G0035562
protein coding gene ChrX:33851795-33859723 (-)
BALB/cJ MGP_BALBcJ_G0035629
protein coding gene ChrX:32808346-32816588 (-)
C3H/HeJ MGP_C3HHeJ_G0035333
protein coding gene ChrX:33398311-33406359 (-)
C57BL/6NJ MGP_C57BL6NJ_G0036159
protein coding gene ChrX:33781794-33789992 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0033011
protein coding gene ChrX:31457942-31464749 (-)
CAST/EiJ MGP_CASTEiJ_G0034623
protein coding gene ChrX:21417831-21424516 (-)
CBA/J MGP_CBAJ_G0035307
protein coding gene ChrX:34623420-34639305 (-)
DBA/2J MGP_DBA2J_G0035461
protein coding gene ChrX:32949092-32956037 (-)
FVB/NJ MGP_FVBNJ_G0035409
protein coding gene ChrX:32677049-32683996 (-)
LP/J MGP_LPJ_G0035549
protein coding gene ChrX:33446822-33457880 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0035448
protein coding gene ChrX:34976913-34983827 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0036176
protein coding gene ChrX:33084659-33094303 (-)
PWK/PhJ MGP_PWKPhJ_G0034324
protein coding gene ChrX:21000882-21008084 (-)
SPRET/EiJ MGP_SPRETEiJ_G0034170
protein coding gene ChrX:21904024-21910198 (-)
WSB/EiJ MGP_WSBEiJ_G0034770
protein coding gene ChrX:32782590-32789590 (-)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000071766 Ensembl Gene Model | MGI Sequence Detail 6831 C57BL/6J ±  kb
transcript ENSMUST00000096453 Ensembl | MGI Sequence Detail 920 Not Applicable  
polypeptide ENSMUSP00000094191 Ensembl | MGI Sequence Detail 186 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    2 Sequences
  • InterPro Domains
    IPR001356 Homeobox domain
    IPR009057 Homeobox-like domain superfamily
    IPR050649 Paired Homeobox Transcription Factors
Molecular
Reagents
less
  • All nucleic 7
    cDNA 7

    Microarray probesets 1
References
more
  • Summaries
    All 18
    Developmental Gene Expression 3
    Gene Ontology 1
    Phenotypes 3
  • Earliest
    J:96937 Maclean JA 2nd, et al., Rhox: a new homeobox gene cluster. Cell. 2005 Feb 11;120(3):369-82
  • Latest
    J:306454 Tan K, et al., The Rhox gene cluster suppresses germline LINE1 transposition. Proc Natl Acad Sci U S A. 2021 Jun 8;118(23):e2024785118

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
11/05/2024
MGI 6.24
The Jackson Laboratory