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Mtx3 Gene Detail
Summary
  • Symbol
    Mtx3
  • Name
    metaxin 3
  • Synonyms
    4930470O13Rik, Gm6514, LOC382793
  • Feature Type
    protein coding gene
  • IDs
    MGI:2686040
    NCBI Gene: 382793
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:92981268-92994738 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 47.78 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    449 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2686040
 protein coding gene Chr13:92981251-92994738 (+)
129S1/SvImJ MGP_129S1SvImJ_G0020821
 protein coding gene Chr13:94172476-94185919 (+)
A/J MGP_AJ_G0020775
 protein coding gene Chr13:90674227-90687664 (+)
AKR/J MGP_AKRJ_G0020748
 protein coding gene Chr13:93415911-93429354 (+)
BALB/cJ MGP_BALBcJ_G0020771
 protein coding gene Chr13:91316885-91330328 (+)
C3H/HeJ MGP_C3HHeJ_G0020565
 protein coding gene Chr13:93128675-93142118 (+)
C57BL/6NJ MGP_C57BL6NJ_G0021208
 protein coding gene Chr13:97038366-97051809 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018775
 protein coding gene Chr13:86592394-86605912 (+)
CAST/EiJ MGP_CASTEiJ_G0020084
 protein coding gene Chr13:92395650-92409076 (+)
CBA/J MGP_CBAJ_G0020524
 protein coding gene Chr13:100862727-100876170 (+)
DBA/2J MGP_DBA2J_G0020649
 protein coding gene Chr13:90437724-90451167 (+)
FVB/NJ MGP_FVBNJ_G0020629
 protein coding gene Chr13:89251874-89265313 (+)
LP/J MGP_LPJ_G0020722
 protein coding gene Chr13:94290306-94303749 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0020658
 protein coding gene Chr13:101368283-101381726 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0021248
 protein coding gene Chr13:92821084-92834527 (+)
PWK/PhJ MGP_PWKPhJ_G0019836
 protein coding gene Chr13:89171474-89184896 (+)
SPRET/EiJ MGP_SPRETEiJ_G0019660
 protein coding gene Chr13:89092809-89106222 (+)
WSB/EiJ MGP_WSBEiJ_G0020141
 protein coding gene Chr13:93308616-93322071 (+)



Homology
more
  • Human Ortholog
    MTX3, metaxin 3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MTX3, metaxin 3
  • Links
    NCBI Gene ID: 345778
    neXtProt AC: NX_Q5HYI7
    UniProt: Q5HYI7

  • Chr Location
    5q14.1; chr5:79976716-79991262 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    6
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000021704 Ensembl Gene Model | MGI Sequence Detail 13471 C57BL/6J ±  kb
transcript ENSMUST00000076169 Ensembl | MGI Sequence Detail 6275 Not Applicable  
polypeptide ENSMUSP00000075526 Ensembl | MGI Sequence Detail 312 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR036282 Glutathione S-transferase, C-terminal domain superfamily
    IPR040079 Glutathione transferase family
    IPR033468 Metaxin, glutathione S-transferase domain
    IPR017410 Mitochondrial outer membrane transport complex protein Metaxin 1/3
    IPR019564 Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain
    IPR050931 Mitochondrial Protein Transport Metaxin
Molecular
Reagents
less
  • All nucleic 6
    cDNA 6

    Microarray probesets 4
Other
Accession IDs
less
MGI:1922212, MGI:2145150, MGI:2145308, MGI:2145382, MGI:3647561
References
more
  • Summaries
    All 26
    Gene Ontology 1
    Phenotypes 6
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:90607 Adolph KW, The zebrafish metaxin 3 gene (mtx3): cDNA and protein structure, and comparison to zebrafish metaxins 1 and 2. Gene. 2004 Apr 14;330:67-73
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory