About   Help   FAQ
Ppp1r37 Gene Detail
Summary
  • Symbol
    Ppp1r37
  • Name
    protein phosphatase 1, regulatory subunit 37
  • Synonyms
    Lrrc68
  • Feature Type
    protein coding gene
  • IDs
    MGI:2687042
    NCBI Gene: 232947
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:19264725-19297001 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 9.93 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    758 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2687042
 protein coding gene Chr7:19264725-19298628 (-)
129S1/SvImJ MGP_129S1SvImJ_G0031783
 protein coding gene Chr7:17556630-17590561 (-)
A/J MGP_AJ_G0031759
 protein coding gene Chr7:17177940-17209078 (-)
AKR/J MGP_AKRJ_G0031685
 protein coding gene Chr7:17654888-17686099 (-)
BALB/cJ MGP_BALBcJ_G0031764
 protein coding gene Chr7:17385509-17417345 (-)
C3H/HeJ MGP_C3HHeJ_G0031486
 protein coding gene Chr7:17916026-17950724 (-)
C57BL/6NJ MGP_C57BL6NJ_G0032230
 protein coding gene Chr7:18421622-18457312 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029296
 protein coding gene Chr7:18826696-18857632 (-)
CAST/EiJ MGP_CASTEiJ_G0030830
 protein coding gene Chr7:14358146-14390300 (-)
CBA/J MGP_CBAJ_G0031448
 protein coding gene Chr7:19092833-19127810 (-)
DBA/2J MGP_DBA2J_G0031603
 protein coding gene Chr7:17129779-17162068 (-)
FVB/NJ MGP_FVBNJ_G0031555
 protein coding gene Chr7:16986818-17020147 (-)
LP/J MGP_LPJ_G0031686
 protein coding gene Chr7:17871268-17905147 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0031591
 protein coding gene Chr7:18932044-18966192 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0032258
 protein coding gene Chr7:17260973-17294098 (-)
PWK/PhJ MGP_PWKPhJ_G0030553
 protein coding gene Chr7:14227469-14261465 (-)
SPRET/EiJ MGP_SPRETEiJ_G0030380
 protein coding gene Chr7:11963643-11996608 (-)
WSB/EiJ MGP_WSBEiJ_G0030929
 protein coding gene Chr7:17485135-17516347 (-)



Homology
more
  • Human Ortholog
    PPP1R37, protein phosphatase 1 regulatory subunit 37
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PPP1R37, protein phosphatase 1 regulatory subunit 37
  • Synonyms
    LRRC68
  • Links
    NCBI Gene ID: 284352
    neXtProt AC: NX_O75864
    UniProt: O75864

  • Chr Location
    19q13.32; chr19:45091396-45148077 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    71
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000051403 Ensembl Gene Model | MGI Sequence Detail 32277 C57BL/6J ±  kb
transcript ENSMUST00000058444 Ensembl | MGI Sequence Detail 3816 Not Applicable  
polypeptide ENSMUSP00000060233 Ensembl | MGI Sequence Detail 712 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000032205 protein phosphatase 1 regulatory subunit 37
    (term hierarchy)
  • InterPro Domains
    IPR001611 Leucine-rich repeat
    IPR032675 Leucine-rich repeat domain superfamily
    IPR051279 Protein Phosphatase 1 Regulatory and Actin Interaction Protein
  • GlyGen
    Q8BKR5 2 sites, 2 N-linked glycans (2 sites)
Molecular
Reagents
less
  • All nucleic 71
    cDNA 71

    Microarray probesets 3
Other
Accession IDs
less
MGI:2685004
References
more
  • Summaries
    All 27
    Gene Ontology 1
    Phenotypes 4
  • Earliest
    J:82808 Strausberg RL, et al., Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903
  • Latest
    J:126097 Cobellis G, et al., Tagging genes with cassette-exchange sites. Nucleic Acids Res. 2005;33(4):e44
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory