Pax6os1 Gene Detail

Summary

• Symbol
  Pax6os1
• Name
  paired box 6 opposite strand 1
• Synonyms
  4831410G09Rik

• Feature Type
  antisense lncRNA gene
  BioType Conflict
  
• IDs
  MGI:3028033
  NCBI Gene: 402728
• Alliance
  gene page
• Transcription Start Sites
  2 TSS

Location &
Maps

• Sequence Map
  Chr2:105366425-105500675 bp, - strand

  From NCBI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 2, 55.25 cM
• Mapping Data
  2 experiments

Strain
Comparison

• SNPs within 2kb
  3184 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_3028033	antisense lncRNA gene	Chr2:105366425-105500675 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0003610	antisense lncRNA gene	Chr2:107702938-107843961 (-)
A/J	MGP_AJ_G0003592	antisense lncRNA gene	Chr2:103216738-103348427 (-)
AKR/J	MGP_AKRJ_G0003570	antisense lncRNA gene	Chr2:106031456-106169594 (-)
BALB/cJ	MGP_BALBcJ_G0003581	antisense lncRNA gene	Chr2:103494601-103625608 (-)
C3H/HeJ	MGP_C3HHeJ_G0003528	antisense lncRNA gene	Chr2:106333128-106467858 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0003719	antisense lncRNA gene	Chr2:111228404-111377347 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0003228	antisense lncRNA gene	Chr2:99016778-99137314 (-)
CAST/EiJ	MGP_CASTEiJ_G0003491	antisense lncRNA gene	Chr2:106867292-106995145 (-)
CBA/J	MGP_CBAJ_G0003525	antisense lncRNA gene	Chr2:115075971-115225616 (-)
DBA/2J	MGP_DBA2J_G0003533	antisense lncRNA gene	Chr2:102757601-102883084 (-)
FVB/NJ	MGP_FVBNJ_G0003553	antisense lncRNA gene	Chr2:101737677-101862902 (-)
LP/J	MGP_LPJ_G0003610	antisense lncRNA gene	Chr2:107833107-107973084 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0003541	antisense lncRNA gene	Chr2:118909761-119043679 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0003721	antisense lncRNA gene	Chr2:106222691-106352999 (-)
PWK/PhJ	MGP_PWKPhJ_G0003446	antisense lncRNA gene	Chr2:102299309-102427483 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0003390	antisense lncRNA gene	Chr2:105450498-105579654 (-)
WSB/EiJ	MGP_WSBEiJ_G0003525	antisense lncRNA gene	Chr2:106963690-107100496 (-)

Homology

• Gene Tree
  Pax6os1
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  1 phenotype from 1 allele in 1 genetic background
  5 phenotype references
  

• All Mutations and Alleles
  5
• Chemically induced (other)
  1
• Endonuclease-mediated
  1
• Radiation induced
  1
• Spontaneous
  2
• Genomic Mutations
  4 involving Pax6os1
• Find Mice (IMSR)
  0 strains or lines available

Mice homozygous for a null allele exhibit normal weight gain, glucose tolerance, and insulin secretion whether fed standard chow or a high-fat diet.

Gene Ontology
(GO)
Classifications

Expression

• Assay Results
  714
• Tissues
  8
• cDNA Data
  1
• Literature Summary
  1

Tissue x Stage Matrix

• Other Mouse Links
  GEO
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  30
• RefSeq
  1

• Ensembl
  ENSMUSG00000086029 (Evidence)
• NCBI Gene
  402728

Representative Sequences			Length	Strain/Species
genomic	402728	NCBI Gene Model | MGI Sequence Detail	134251	C57BL/6J
transcript	NR_002867	RefSeq | MGI Sequence Detail	1464	C57BL/6

Molecular
Reagents

• All nucleic 2

  cDNA 1

  Primer pair 1

  
  

  Microarray probesets 1

References

• Summaries
  All 16

  Developmental Gene Expression 1

  Phenotypes 5
• Earliest
  J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
• Latest
  J:319562 Lopez-Noriega L, et al., The long non-coding RNA Pax6os1/PAX6-AS1 modulates pancreatic beta-cell identity and function. bioRxiv. 2021 Jan;

TSS for Pax6os1:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr25563	Chr2:105500646-105500667 (-)	18 bp
Tssr25562	Chr2:105500636-105500643 (-)	35 bp