Pramel3e Gene Detail

Summary

• Symbol
  Pramel3e
• Name
  PRAME like 3E
• Synonyms
  AV320801

• Feature Type
  protein coding gene
• IDs
  MGI:3035227
  NCBI Gene: 331531
• Alliance
  gene page

Location &
Maps

• Sequence Map
  ChrX:134395337-134405343 bp, + strand

  From Ensembl annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome X, 57.12 cM
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  5 from dbSNP Build 142
• Strain Annotations
  9

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_3035227	protein coding gene	ChrX:134395314-134405504 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0036084	protein coding gene	ChrX:132800117-132815049 (+)
A/J	no annotation
AKR/J	MGP_AKRJ_G0035988	protein coding gene	ChrX:136446583-136456223 (+)
BALB/cJ	no annotation
C3H/HeJ	no annotation
C57BL/6NJ	no annotation
CAROLI/EiJ	no annotation
CAST/EiJ	MGP_CASTEiJ_G0035046	protein coding gene	ChrX:113488235-113494063 (+)
CBA/J	no annotation
DBA/2J	no annotation
FVB/NJ	no annotation
LP/J	MGP_LPJ_G0035984	protein coding gene	ChrX:133642205-133734247 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0035863	protein coding gene	ChrX:148154826-148164434 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0036606	protein coding gene	ChrX:131816678-131827799 (-)
PWK/PhJ	MGP_PWKPhJ_G0034739	protein coding gene	ChrX:110431143-110436699 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0034571	protein coding gene	ChrX:114292378-114306893 (+)
WSB/EiJ	no annotation

Homology

• MGI Vertebrate Homology
  Pramel3e stringent orthology
  1 mouse;1 rat
  
• Gene Tree
  Pramel3e
  

Human Diseases

• References
  1 with disease annotations

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  2 phenotype references
  

• All Mutations and Alleles
  1
• Targeted
  1
• Genomic Mutations
  1 involving Pramel3e
• Find Mice (IMSR)
  1 strains or lines available

Gene Ontology
(GO)
Classifications

Expression

• Assay Results
  706
• cDNA Data
  1

Tissue x Stage Matrix

• Other Mouse Links
  GEO
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  20
• RefSeq
  4
• UniProt
  1
• CCDS
  CCDS53189.1

• Ensembl
  ENSMUSG00000054994 (Evidence)
• NCBI Gene
  331531

Representative Sequences			Length	Strain/Species
genomic	ENSMUSG00000054994	Ensembl Gene Model | MGI Sequence Detail	10007	C57BL/6J
transcript	ENSMUST00000068340	Ensembl | MGI Sequence Detail	3698	Not Applicable
polypeptide	ENSMUSP00000068753	Ensembl | MGI Sequence Detail	462	Not Applicable

Protein
Information

• UniProt
  1 Sequence
• InterPro Domains
  IPR032675 Leucine-rich repeat domain superfamily
  IPR050694 PRAME domain-containing protein

Molecular
Reagents

• All nucleic 1

  cDNA 1

  
  

  Microarray probesets 1

Other
Accession IDs

MGI:7466573

References

• Summaries
  All 14

  Diseases 1

  Phenotypes 2
• Earliest
  J:199138 Zhou J, et al., A 1.1-Mb segmental deletion on the X chromosome causes meiotic failure in male mice. Biol Reprod. 2013 Jun;88(6):159
• Latest
  J:210663 Zhou J, et al., Respiratory failure, cleft palate and epilepsy in the mouse model of human Xq22.1 deletion syndrome. Hum Mol Genet. 2014 Jul 15;23(14):3823-9