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Frg2f1 Gene Detail
Summary
  • Symbol
    Frg2f1
  • Name
    FSHD region gene 2 family member 1
  • Synonyms
    AA415398
  • Feature Type
    protein coding gene
  • IDs
    MGI:3035485
    NCBI Gene: 433752
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:119387505-119395966 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 55.43 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    297 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3035485
 protein coding gene Chr4:119387505-119396726 (-)
129S1/SvImJ MGP_129S1SvImJ_G0028701
 protein coding gene Chr4:120733387-120742700 (-)
A/J MGP_AJ_G0028661
 protein coding gene Chr4:115992625-116001628 (-)
AKR/J MGP_AKRJ_G0028614
 protein coding gene Chr4:118508366-118518869 (-)
BALB/cJ MGP_BALBcJ_G0028684
 protein coding gene Chr4:116623359-116632495 (-)
C3H/HeJ MGP_C3HHeJ_G0028399
 protein coding gene Chr4:120074349-120084922 (-)
C57BL/6NJ MGP_C57BL6NJ_G0029125
 protein coding gene Chr4:125314160-125324587 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026402
 protein coding gene Chr4:110082917-110092023 (-)
CAST/EiJ MGP_CASTEiJ_G0027830
 protein coding gene Chr4:117399324-117409297 (-)
CBA/J MGP_CBAJ_G0028366
 protein coding gene Chr4:128714442-128723761 (-)
DBA/2J MGP_DBA2J_G0028513
 protein coding gene Chr4:116579998-116589001 (-)
FVB/NJ MGP_FVBNJ_G0028479
 protein coding gene Chr4:115098001-115107005 (-)
LP/J MGP_LPJ_G0028613
 protein coding gene Chr4:120855698-120865453 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0028507
 protein coding gene Chr4:133591444-133601488 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0029162
 protein coding gene Chr4:119584972-119595494 (-)
PWK/PhJ MGP_PWKPhJ_G0027553
 protein coding gene Chr4:113504306-113514740 (-)
SPRET/EiJ MGP_SPRETEiJ_G0027379
 protein coding gene Chr4:115998540-116007628 (-)
WSB/EiJ MGP_WSBEiJ_G0027910
 protein coding gene Chr4:119592477-119603266 (-)



Homology
more
  • Human Ortholog
    FRG2, FSHD region gene 2
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FRG2, FSHD region gene 2
  • Synonyms
    FRG2A
  • Links
    NCBI Gene ID: 448831
    neXtProt AC: NX_Q64ET8
    UniProt: Q64ET8

  • Chr Location
    4q35.2; chr4:190024367-190027257 (-)  GRCh38
  • Human Ortholog
    FRG2B, FSHD region gene 2 family member B
  • Links
    NCBI Gene ID: 441581
    neXtProt AC: NX_Q96QU4
    UniProt: Q96QU4

  • Chr Location
    10q26.3; chr10:133623895-133626795 (-)  GRCh38
  • Human Ortholog
    FRG2C, FSHD region gene 2 family member C
  • Links
    NCBI Gene ID: 100288801
    neXtProt AC: NX_A6NGY1
    UniProt: A6NGY1

  • Chr Location
    chr3:75664328-75667220 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
  • All Mutations and Alleles
    6
  • Chemically induced (other)
    2
  • Endonuclease-mediated
    2
  • Radiation induced
    1
  • Targeted
    1
  • Genomic Mutations
    4 involving Frg2f1
  • Incidental Mutations
    APF , CvDC
  • Find Mice (IMSR)
    9 strains or lines available
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    15
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 433752 NCBI Gene Model | MGI Sequence Detail 8462 C57BL/6J ±  kb
transcript NM_001004178 RefSeq | MGI Sequence Detail 1919 C57BL/6  
polypeptide NP_001004178 RefSeq | MGI Sequence Detail 227 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR026245 Protein FRG2
Molecular
Reagents
less
  • All nucleic 15
    cDNA 15

    Microarray probesets 2
References
more
  • Summaries
    All 25
    Phenotypes 8
  • Earliest
    J:84714 Nishijima I, et al., Two new balancer chromosomes on mouse chromosome 4 to facilitate functional annotation of human chromosome 1p. Genesis. 2003 Jul;36(3):142-8
  • Latest
    J:148802 Boles MK, et al., A mouse chromosome 4 balancer ENU-mutagenesis screen isolates eleven lethal lines. BMC Genet. 2009;10:12
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory