Apol10a MGI Mouse Gene Detail - MGI:3036238

Symbol

Apol10a
Name

apolipoprotein L 10A
Synonyms

9030421J09Rik

Feature Type

protein coding gene
IDs

MGI:3036238
NCBI Gene: 245282
Alliance

gene page
Transcription Start Sites

1 TSS

Sequence Map

Chr15:77361247-77375269 bp, + strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 15, 36.40 cM
Mapping Data

1 experiment

SNPs within 2kb

484 from dbSNP Build 142
Strain Annotations

10

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_3036238	protein coding gene	Chr15:77361153-77375269 (+)
129S1/SvImJ	no annotation
A/J	MGP_AJ_G0021985	protein coding gene	Chr15:74778472-74782961 (+)
AKR/J	no annotation
BALB/cJ	MGP_BALBcJ_G0021990	protein coding gene	Chr15:74891081-74896968 (+)
C3H/HeJ	no annotation
C57BL/6NJ	MGP_C57BL6NJ_G0022430	protein coding gene	Chr15:80537592-80589788 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0019967	protein coding gene	Chr15:71630085-71640170 (-)
CAST/EiJ	MGP_CASTEiJ_G0021284	protein coding gene	Chr15:77669927-77687126 (+)
CBA/J	no annotation
DBA/2J	no annotation
FVB/NJ	no annotation
LP/J	MGP_LPJ_G0021929	protein coding gene	Chr15:77906423-77912351 (-)
NOD/ShiLtJ	no annotation
NZO/HlLtJ	no annotation
PWK/PhJ	MGP_PWKPhJ_G0021028	protein coding gene	Chr15:74498955-74509547 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0020864	protein coding gene	Chr15:76874594-76893386 (+)
WSB/EiJ	MGP_WSBEiJ_G0021337	protein coding gene	Chr15:77548347-77551481 (-)

Human Ortholog

APOL1, apolipoprotein L1

Vertebrate Orthologs

4

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

APOL1, apolipoprotein L1
Synonyms

APO-L, APOL, APOL-I, FSGS4
Links

HGNC:618

NCBI Gene ID: 8542

neXtProt AC: NX_O14791

UniProt: O14791
Chr Location

22q12.3; chr22:36253071-36267530 (+) GRCh38

Human Ortholog

APOL2, apolipoprotein L2
Synonyms

APOL3, APOL-II
Links

HGNC:619

NCBI Gene ID: 23780

neXtProt AC: NX_Q9BQE5

UniProt: Q9BQE5
Chr Location

22q12.3; chr22:36226209-36239954 (-) GRCh38

MGI Vertebrate Homology

Apol10a stringent orthology
2 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: APOL1, APOL2
Gene Tree

Apol10a

Diseases

1 with human APOL2,APOL4 associations

				Human Disease	Mouse Models
				schizophrenia IDs schizophrenia DOID:5419 DOID:14734 ICD10CM:F20 ICD9CM:295 ICD9CM:295.8 ICD9CM:295.80 ICD9CM:295.9 ICD9CM:295.90 MESH:D012559 NCI:C3362 OMIM:181500 UMLS_CUI:C0036341

Click on a disease name to see all genes associated with that disease.

References

1 with disease annotations

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Phenotype Summary

24 phenotype references

All Mutations and Alleles

7
Chemically induced (other)

2
Radiation induced

2
Targeted

3
Genomic Mutations

4 involving Apol10a
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

17 strains or lines available

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All GO Annotations

6
GO References

2

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

706
cDNA Data

3

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas

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All Sequences

20
RefSeq

4
UniProt

1
CCDS

CCDS27601.1

Ensembl

ENSMUSG00000050982 (Evidence)
NCBI Gene

245282

			Length	Strain/Species	Flank
genomic	ENSMUSG00000050982	Ensembl Gene Model \| MGI Sequence Detail	14023	C57BL/6J	± kb
transcript	ENSMUST00000060551	Ensembl \| MGI Sequence Detail	3033	Not Applicable
polypeptide	ENSMUSP00000060650	Ensembl \| MGI Sequence Detail	318	Not Applicable

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UniProt

1 Sequence
InterPro Domains

IPR008405 Apolipoprotein L

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All nucleic 3

cDNA 3

Microarray probesets 1

Summaries

All 40

Diseases 1

Gene Ontology 2

Phenotypes 24
Earliest

J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
Latest

J:285676 Suzuki A, et al., Genes and microRNAs associated with mouse cleft palate: A systematic review and bioinformatics analysis. Mech Dev. 2018 Apr;150:21-27

TSS for Apol10a:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr131865	Chr15:77361244-77361248 (+)	-1 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24