nm3 Gene Detail

Summary

• Symbol
  nm3
• Name
  neurological mutant 3

• Feature Type
  heritable phenotypic marker
• IDs
  MGI:3038234
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Chr2:63752422-67923278 bp

  From MGI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 2, Syntenic
• Mapping Data
  1 experiment

Human Diseases

• Diseases
  1 with nm3 mouse models

Human Disease

Mouse Models

Parkinson's disease

IDs

Parkinson's disease      

DOID:14330
ICD10CM:G20
ICD9CM:332
ICD9CM:332.0
KEGG:05012
MESH:D010300
NCI:C26845
OMIM:PS168600
ORDO:2828
UMLS_CUI:C0030567

View 1 model

Mouse Models

Human Disease Modeled: Parkinson's disease

Allelic Composition	Genetic Background	Reference	Phenotypes
nm3/nm3	involves: RIIIS/J	J:88298	View

Click on a disease name to see all genes associated with that disease.

• Mutations/Alleles
  1 with disease annotations

• References
  1 with disease annotations

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  9 phenotypes from 1 allele in 1 genetic background
  1 phenotype reference
  

• All Mutations and Alleles
  1
• Spontaneous
  1
• Find Mice (IMSR)
  0 strains or lines available

Mutant mice display a movement phenotype characterized by bradykinesia and jerky movement typical of Parkinson's Disease. Homozygous mice do not survive past weaning.

References

• Summaries
  All 1

  Diseases 1

  Phenotypes 1
• Earliest
  J:88298 Legare ME, et al., Genetic, biochemical, and characterization of neurological mutant 3, a new mouse model for Parkinson's disease. Genet Mol Res. 2003 Sep 30;2(3):288-94