Tg(C3-1-TAg)cJeg
Transgene Detail

Summary

• Symbol: Tg(C3-1-TAg)cJeg
• Name: transgene insertion c, Jeffrey E Green
• MGI ID: MGI:3039067
• Synonyms: C3(1)/SV40, C3(1)/SV40T, C3(1)-SV40 T antigen, C3(1)-Tag, C3(1)/Tag, C3(1)/TAg, C3(1)/T(AG), C3(1)/T antigen (Tag), C3-TAg, C3Tag, Large T, Tg(Scgb2a2-TAg)cJeg
• Transgene: Tg(C3-1-TAg)cJeg Location: unknown
• Alliance: Tg(C3-1-TAg)cJeg page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: This transgene contains the rat prostatic binding protein C3 promoter (Pbpc3) and the wild-type allele of the SV40 large tumor antigen (TAg) gene. Founder c carried 6 copies of the transgene. Founders f, g, i, j, k, and l were also generated. Two transgenic lines (c and l) were produced. (J:52786)

Disease models

Expression

In Structures Affected by this Mutation:

6 anatomical structure(s)

Tumor Data

List all tumor models in MMHCdb carrying Tg(C3-1-TAg)cJeg

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available

References

• Original: J:52786 Maroulakou IG, et al., Prostate and mammary adenocarcinoma in transgenic mice carrying a rat C3(1) simian virus 40 large tumor antigen fusion gene. Proc Natl Acad Sci U S A. 1994 Nov 8;91(23):11236-40
• All: 97 reference(s)