Ccdc148 MGI Mouse Gene Detail - MGI:3039583 - coiled-coil domain containing 148

Symbol

Ccdc148
Name

coiled-coil domain containing 148

Feature Type

protein coding gene
IDs

MGI:3039583
NCBI Gene: 227933
Alliance

gene page
Transcription Start Sites

3 TSS

Sequence Map

Chr2:58711082-58991027 bp, - strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 2, 33.30 cM
Mapping Data

1 experiment

SNPs within 2kb

7631 from dbSNP Build 142
Strain Annotations

8

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_3039583	protein coding gene	Chr2:58701637-58991167 (-)
129S1/SvImJ	no annotation
A/J	no annotation
AKR/J	no annotation
BALB/cJ	MGP_BALBcJ_G0025723	protein coding gene	Chr2:56248952-56522661 (-)
C3H/HeJ	no annotation
C57BL/6NJ	no annotation
CAROLI/EiJ	MGP_CAROLIEiJ_G0023575	protein coding gene	Chr2:53726822-53994252 (-)
CAST/EiJ	MGP_CASTEiJ_G0024949	protein coding gene	Chr2:57800398-58080911 (-)
CBA/J	no annotation
DBA/2J	MGP_DBA2J_G0025595	protein coding gene	Chr2:55761054-56031676 (-)
FVB/NJ	no annotation
LP/J	no annotation
NOD/ShiLtJ	no annotation
NZO/HlLtJ	MGP_NZOHlLtJ_G0026227	protein coding gene	Chr2:57691438-57982806 (-)
PWK/PhJ	MGP_PWKPhJ_G0024690	protein coding gene	Chr2:55573365-55841975 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0024496	protein coding gene	Chr2:57776968-58057835 (-)
WSB/EiJ	no annotation

Human Ortholog

CCDC148, coiled-coil domain containing 148

Vertebrate Orthologs

2

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

CCDC148, coiled-coil domain containing 148
Links

HGNC:25191

NCBI Gene ID: 130940

neXtProt AC: NX_Q8NFR7

UniProt: Q8NFR7
Chr Location

2q24.1; chr2:158171073-158456753 (-) GRCh38

MGI Vertebrate Homology

Ccdc148 stringent orthology
1 human;1 mouse;1 rat
HCOP

vertebrate homology predictions: CCDC148
Gene Tree

Ccdc148

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Phenotype Summary

1 phenotype from 1 allele in 1 genetic background
5 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

3
Chemically induced (other)

1
Endonuclease-mediated

2
Genomic Mutations

1 involving Ccdc148
Incidental Mutations

Mutagenetix , APF , CvDC
Find Mice (IMSR)

32 strains or lines available

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Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.

Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.

Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

725
Tissues

8
cDNA Data

5
Literature Summary

1

Images

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase ccdc148

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All Sequences

43
RefSeq

20
UniProt

2
CCDS

CCDS50587.1, CCDS89489.1

Ensembl

ENSMUSG00000036641 (Evidence)
NCBI Gene

227933

			Length	Strain/Species	Flank
genomic	ENSMUSG00000036641	Ensembl Gene Model \| MGI Sequence Detail	279946	C57BL/6J	± kb
transcript	ENSMUST00000226455	Ensembl \| MGI Sequence Detail	4612	Not Applicable
polypeptide	ENSMUSP00000153944	Ensembl \| MGI Sequence Detail	599	Not Applicable

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UniProt

2 Sequences
Protein Ontology

PR:000031245 coiled-coil domain-containing protein 148

(term hierarchy)
InterPro Domains

IPR039902 Coiled-coil domain-containing protein CCDC148/CCDC112

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All nucleic 5

cDNA 5

Microarray probesets 1

Summaries

All 20

Developmental Gene Expression 1

Phenotypes 5
Earliest

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
Latest

J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

TSS for Ccdc148:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr24159	Chr2:58990988-58991007 (-)	29 bp
Tssr24158	Chr2:58990968-58990979 (-)	53 bp
Tssr24157	Chr2:58985056-58985062 (-)	5,968 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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