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Tg(WapTAg)1Knw
Transgene Detail
Summary
Symbol: Tg(WapTAg)1Knw
Name: transgene insertion 1, Barbara B Knowles
MGI ID: MGI:3040314
Synonyms: WAPTag 1
Transgene: Tg(WapTAg)1Knw  Location: unknown  
Alliance: Tg(WapTAg)1Knw page
Transgene
origin
Strain of Origin:  C57BL/6J
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Mutation detailsThe transgene contains the mouse Wap (whey acidic protein) promoter and the wild-type allele of the SV40 large T antigen (Tag) gene. (J:53175)
Phenotypes
Key:
hm homozygous ht heterozygous tg involves transgenes phenotype observed
cn conditional genotype  cx complex: > 1 genome feature ot other: hemizygous, indeterminate,... N normal phenotype
Genotype/
Background:
Allelic Composition
Genetic Background
Cell Line(s)
tg1  Disease Model
 
Phenotypes:
Affected Systems
show or hide all annotated terms
 
endocrine/exocrine glands
increased mammary adenocarcinoma incidence
integument
increased mammary adenocarcinoma incidence
neoplasm
increased mammary adenocarcinoma incidence
increased sarcoma incidence
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
Key:
disease model   expected model not found
Models:
Human Diseases
tg1
IDs
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Tumor Data
List all tumor models in MMHCdb carrying Tg(WapTAg)1Knw
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:53175 Husler MR, et al., Lactation-induced WAP-SV40 Tag transgene expression in C57BL/6J mice leads to mammary carcinoma. Transgenic Res. 1998 Jul;7(4):253-63
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory