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Shisa3 Gene Detail
Summary
  • Symbol
    Shisa3
  • Name
    shisa family member 3
  • Synonyms
    D830007B15Rik, mShisa3
  • Feature Type
    protein coding gene
  • IDs
    MGI:3041225
    NCBI Gene: 330096
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:67765226-67771330 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 36.15 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    227 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3041225
 protein coding gene Chr5:67765225-67780895 (+)
129S1/SvImJ MGP_129S1SvImJ_G0029596
 protein coding gene Chr5:67390356-67407332 (+)
A/J MGP_AJ_G0029564
 protein coding gene Chr5:64867948-64885403 (+)
AKR/J MGP_AKRJ_G0029512
 protein coding gene Chr5:66945295-66961771 (+)
BALB/cJ MGP_BALBcJ_G0029573
 protein coding gene Chr5:65540471-65556172 (+)
C3H/HeJ MGP_C3HHeJ_G0029296
 protein coding gene Chr5:67261446-67277088 (+)
C57BL/6NJ MGP_C57BL6NJ_G0030027
 protein coding gene Chr5:70170993-70186662 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0027267
 protein coding gene Chr5:60910217-60926346 (+)
CAST/EiJ MGP_CASTEiJ_G0028704
 protein coding gene Chr5:66466507-66482217 (+)
CBA/J MGP_CBAJ_G0029265
 protein coding gene Chr5:72422400-72438052 (+)
DBA/2J MGP_DBA2J_G0029411
 protein coding gene Chr5:64878880-64894535 (+)
FVB/NJ MGP_FVBNJ_G0029371
 protein coding gene Chr5:64050885-64067234 (+)
LP/J MGP_LPJ_G0029496
 protein coding gene Chr5:67882801-67900592 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0029399
 protein coding gene Chr5:75224272-75241175 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0030060
 protein coding gene Chr5:66612430-66628067 (+)
PWK/PhJ MGP_PWKPhJ_G0028428
 protein coding gene Chr5:63921120-63938059 (+)
SPRET/EiJ MGP_SPRETEiJ_G0028262
 protein coding gene Chr5:65946268-65961948 (+)
WSB/EiJ MGP_WSBEiJ_G0028784
 protein coding gene Chr5:66841149-66858008 (+)



Homology
more
  • Human Ortholog
    SHISA3, shisa family member 3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SHISA3, shisa family member 3
  • Synonyms
    hShisa3
  • Links
    NCBI Gene ID: 152573
    neXtProt AC: NX_A0PJX4
    UniProt: A0PJX4

  • Chr Location
    4p13; chr4:42397488-42402487 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    22 phenotype references
  • All Mutations and Alleles
    10
  • Chemically induced (other)
    2
  • Radiation induced
    1
  • Spontaneous
    1
  • Targeted
    6
  • Genomic Mutations
    4 involving Shisa3
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    12 strains or lines available
Mice homozygous for a targeted null mutation are viable, fertile and apparently normal with no defects in head development.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    807
  • Tissues
    31
  • cDNA Data
    9
  • Literature Summary
    5
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 330096 NCBI Gene Model | MGI Sequence Detail 6105 C57BL/6J ±  kb
transcript NM_001033415 RefSeq | MGI Sequence Detail 3754 C57BL/6  
polypeptide Q3UPR0 UniProt | EBI | MGI Sequence Detail 238 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 9
    cDNA 9

    Microarray probesets 5
References
more
  • Summaries
    All 43
    Developmental Gene Expression 5
    Gene Ontology 2
    Phenotypes 22
  • Earliest
    J:5021 Batchelor AL, et al., A comparison of the mutagenic effectiveness of chronic neutron- and gamma-irradiation of mouse spermatogonia. Mutat Res. 1966 Jun;3(3):218-29
  • Latest
    J:294316 Murakami K, et al., The Shisa3 knockout mouse exhibits normal bone phenotype. J Bone Miner Metab. 2019 Nov;37(6):967-975
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory