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Rsl1 Gene Detail
Summary
  • Symbol
    Rsl1
  • Name
    regulator of sex limited protein 1
  • Synonyms
    rslcan-9
  • Feature Type
    protein coding gene
  • IDs
    MGI:3044162
    NCBI Gene: 380855
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:67321238-67332108 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 13, 34.54 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    597 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3044162
protein coding gene Chr13:67321195-67332108 (+)
129S1/SvImJ MGP_129S1SvImJ_G0020702
protein coding gene Chr13:67310655-67319203 (+)
A/J MGP_AJ_G0020664
protein coding gene Chr13:65076655-65085628 (-)
AKR/J MGP_AKRJ_G0020634
protein coding gene Chr13:67023638-67033672 (+)
BALB/cJ MGP_BALBcJ_G0020662
protein coding gene Chr13:65521777-65532453 (-)
C3H/HeJ MGP_C3HHeJ_G0020448
protein coding gene Chr13:66636993-66661333 (+)
C57BL/6NJ MGP_C57BL6NJ_G0021098
protein coding gene Chr13:69937757-69942307 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018669
protein coding gene Chr13:62676406-62686702 (-)
CAST/EiJ MGP_CASTEiJ_G0019966
protein coding gene Chr13:65860844-65870362 (+)
CBA/J MGP_CBAJ_G0020408
protein coding gene Chr13:72149048-72160919 (+)
DBA/2J MGP_DBA2J_G0020531
protein coding gene Chr13:64718883-64728566 (+)
FVB/NJ MGP_FVBNJ_G0020521
protein coding gene Chr13:63981461-63989305 (-)
LP/J no annotation
NOD/ShiLtJ MGP_NODShiLtJ_G0020549
protein coding gene Chr13:71185211-71252415 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0021138
protein coding gene Chr13:66461235-66473646 (-)
PWK/PhJ MGP_PWKPhJ_G0019729
protein coding gene Chr13:63911725-63922201 (-)
SPRET/EiJ MGP_SPRETEiJ_G0019548
protein coding gene Chr13:63322822-63524886 (-)
WSB/EiJ MGP_WSBEiJ_G0020028
protein coding gene Chr13:66735250-66780841 (+)



Homology
more
  • Human Ortholog
    ZNF429, zinc finger protein 429
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZNF429, zinc finger protein 429
  • Links
    NCBI Gene ID: 353088
    neXtProt AC: NX_Q86V71
    UniProt: Q86V71

  • Chr Location
    19p12; chr19:21496682-21556270 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 380855 NCBI Gene Model | MGI Sequence Detail 10871 C57BL/6J ±  kb
transcript NM_001013769 RefSeq | MGI Sequence Detail 2599 ZRU/MplStud  
polypeptide NP_001013791 RefSeq | MGI Sequence Detail 472 ZRU/MplStud  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 4
    cDNA 4

    Microarray probesets 2
References
more
  • Summaries
    All 22
    Gene Ontology 3
    Phenotypes 5
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:207685 Krebs CJ, et al., The KRAB zinc finger protein RSL1 modulates sex-biased gene expression in liver and adipose tissue to maintain metabolic homeostasis. Mol Cell Biol. 2014 Jan;34(2):221-32

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory