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Tlr11 Gene Detail
Summary
  • Symbol
    Tlr11
  • Name
    toll-like receptor 11
  • Synonyms
    LOC239081
  • Feature Type
    protein coding gene
  • IDs
    MGI:3045226
    NCBI Gene: 239081
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:50595371-50601120 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 14, 26.07 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    200 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3045226
 protein coding gene Chr14:50595371-50601120 (+)
129S1/SvImJ MGP_129S1SvImJ_G0021245
 protein coding gene Chr14:44270171-44275930 (+)
A/J MGP_AJ_G0021196
 protein coding gene Chr14:42942809-42948568 (+)
AKR/J MGP_AKRJ_G0021173
 protein coding gene Chr14:44583276-44594746 (+)
BALB/cJ MGP_BALBcJ_G0021200
 protein coding gene Chr14:43050873-43056632 (+)
C3H/HeJ MGP_C3HHeJ_G0020982
 protein coding gene Chr14:44387377-44393136 (+)
C57BL/6NJ MGP_C57BL6NJ_G0021635
 protein coding gene Chr14:46118573-46124322 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0019192
 protein coding gene Chr14:42323576-42329328 (+)
CAST/EiJ MGP_CASTEiJ_G0020507
 protein coding gene Chr14:41459037-41464788 (+)
CBA/J MGP_CBAJ_G0020950
 protein coding gene Chr14:47538395-47545500 (+)
DBA/2J MGP_DBA2J_G0021072
 protein coding gene Chr14:42837564-42843320 (+)
FVB/NJ MGP_FVBNJ_G0021056
 protein coding gene Chr14:42510911-42516691 (+)
LP/J MGP_LPJ_G0021141
 protein coding gene Chr14:44553844-44559591 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0021081
 protein coding gene Chr14:46963618-46969446 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0021667
 protein coding gene Chr14:44065878-44071642 (+)
PWK/PhJ MGP_PWKPhJ_G0020256
 protein coding gene Chr14:39739201-39745277 (+)
SPRET/EiJ MGP_SPRETEiJ_G0020082
 protein coding gene Chr14:40220252-40229149 (+)
WSB/EiJ MGP_WSBEiJ_G0020564
 protein coding gene Chr14:44207633-44214183 (+)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    11
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    7
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 239081 NCBI Gene Model | MGI Sequence Detail 5750 C57BL/6J ±  kb
transcript NM_205819 RefSeq | MGI Sequence Detail 3212 C57BL/6  
polypeptide Q6R5P0 UniProt | EBI | MGI Sequence Detail 926 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 7
    cDNA 7

    Microarray probesets 1
Other
Accession IDs
less
MGI:2685133
References
more
  • Summaries
    All 47
    Developmental Gene Expression 1
    Gene Ontology 7
    Phenotypes 8
  • Earliest
    J:88906 Tabeta K, et al., Toll-like receptors 9 and 3 as essential components of innate immune defense against mouse cytomegalovirus infection. Proc Natl Acad Sci U S A. 2004 Mar 9;101(10):3516-21
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory