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Krt90 Gene Detail
Summary
  • Symbol
    Krt90
  • Name
    keratin 90
  • Synonyms
    4732456N10Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:3045312
    NCBI Gene: 239673
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:101460791-101471385 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 56.90 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    377 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3045312
 protein coding gene Chr15:101460791-101471385 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022379
 protein coding gene Chr15:103652794-103663353 (-)
A/J MGP_AJ_G0022341
 protein coding gene Chr15:99536034-99546611 (-)
AKR/J MGP_AKRJ_G0022317
 protein coding gene Chr15:102575867-102586428 (-)
BALB/cJ MGP_BALBcJ_G0022345
 protein coding gene Chr15:99645694-99656256 (-)
C3H/HeJ MGP_C3HHeJ_G0022113
 protein coding gene Chr15:102669201-102679778 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022793
 protein coding gene Chr15:107519718-107532090 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020318
 protein coding gene Chr15:95390950-95401246 (-)
CAST/EiJ MGP_CASTEiJ_G0021639
 protein coding gene Chr15:103520733-103531313 (-)
CBA/J MGP_CBAJ_G0022083
 protein coding gene Chr15:111255235-111265811 (-)
DBA/2J MGP_DBA2J_G0022211
 protein coding gene Chr15:98862849-98873620 (-)
FVB/NJ MGP_FVBNJ_G0022190
 protein coding gene Chr15:97925167-97935739 (-)
LP/J MGP_LPJ_G0022281
 protein coding gene Chr15:103805258-103818778 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022211
 protein coding gene Chr15:114902298-114913587 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022807
 protein coding gene Chr15:102617832-102628407 (-)
PWK/PhJ MGP_PWKPhJ_G0021378
 protein coding gene Chr15:99036914-99047472 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021210
 protein coding gene Chr15:102502376-102512867 (-)
WSB/EiJ MGP_WSBEiJ_G0021689
 protein coding gene Chr15:103259999-103271970 (-)



Homology
more
  • Human Ortholog
    KRT90P, keratin 90, pseudogene
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    KRT90P, keratin 90, pseudogene
  • Synonyms
    HBA, KRT124P, KRTHBP1
  • Links
    NCBI Gene ID: 85340

  • Chr Location
    12q13.13; chr12:52411742-52421867 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    7 phenotypes from 2 alleles in 3 genetic backgrounds
    3 images
    33 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a spontaneous mutation exhibit partial prenatal lethality and thickened long toenails. An increased caudal vertebrae number is observed in some mutant mice.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    4
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    4
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 239673 NCBI Gene Model | MGI Sequence Detail 10595 C57BL/6J ±  kb
    transcript NM_177717 RefSeq | MGI Sequence Detail 2534 C57BL/6  
    polypeptide NP_808385 RefSeq | MGI Sequence Detail 538 C57BL/6  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      3 Sequences
    • InterPro Domains
      IPR018039 Intermediate filament protein, conserved site
      IPR039008 Intermediate filament, rod domain
      IPR003054 Keratin, type II
      IPR032444 Keratin type II head
    • GlyGen
      E9Q1Z0 1 site, 1 O-linked glycan (1 site)
    Molecular
    Reagents
    less
    • All nucleic 4
      cDNA 4

      Microarray probesets 1
    References
    more
    • Summaries
      All 46
      Diseases 1
      Gene Ontology 1
      Phenotypes 33
    • Earliest
      J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory