Srcr Gene Detail

Summary

• Symbol
  Srcr
• Name
  spontaneous regression or complete resistance
• Synonyms
  SR/CR

• Feature Type
  heritable phenotypic marker
• IDs
  MGI:3045947
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome Unknown

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  2 phenotypes from 1 allele in 3 genetic backgrounds
  1 phenotype from multigenic genotypes
  4 phenotype references
  

• All Mutations and Alleles
  1
• Spontaneous
  1
• Find Mice (IMSR)
  0 strains or lines available

Heterozygous mice display spontaneous regression of or complete resistance to tumor formation after injection of tumor forming cells.

References

• Summaries
  All 4

  Phenotypes 4
• Earliest
  J:83618 Cui Z, et al., Spontaneous regression of advanced cancer: identification of a unique genetically determined, age-dependent trait in mice. Proc Natl Acad Sci U S A. 2003 May 27;100(11):6682-7
• Latest
  J:107883 Hicks AM, et al., Transferable anticancer innate immunity in spontaneous regression/complete resistance mice. Proc Natl Acad Sci U S A. 2006 May 16;103(20):7753-8