Tg(Ttr-cre/Esr1*)1Vco
Transgene Detail

Summary

• Symbol: Tg(Ttr-cre/Esr1*)1Vco
• Name: transgene insertion 1, Mireille Vasseur-Cognet
• MGI ID: MGI:3046546
• Synonyms: B line, Tg(Ttr-cre/Esr1)1Vco, TTR-Cre ind, TTR-Cre^Tam, TTR-MerCreMer
• Transgene: Tg(Ttr-cre/Esr1*)1Vco Location: unknown
• Alliance: Tg(Ttr-cre/Esr1*)1Vco page

Transgene origin

• Strain of Origin: (C57BL/6 x DBA/2)F1

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Tg(Ttr-cre/Esr1*)1Vco expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Ttr (MGI:98865)

• Mutation details: This transgene expresses a Cre recombinase/hormone-binding domain of the mouse estrogen receptor gene fusion under the control of a mouse transthyretin promoter. Expression of this inducible form of Cre recombinase was detected in fetal and adult liver. (J:82537)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Ttr (mouse) Summary of all recombinase alleles driven by Ttr. Comparative matrix view of recombinase activities Alliance mouse Ttr gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:82537 Tannour-Louet M, et al., A tamoxifen-inducible chimeric Cre recombinase specifically effective in the fetal and adult mouse liver. Hepatology. 2002 May;35(5):1072-81
• All: 22 reference(s)