Tg(MtTPRMET)243Lng
Transgene Detail

Summary

• Symbol: Tg(MtTPRMET)243Lng
• Name: transgene insertion 243, T Jake Liang
• MGI ID: MGI:3054048
• Synonyms: MTM1
• Transgene: Tg(MtTPRMET)243Lng Location: unknown
• Alliance: Tg(MtTPRMET)243Lng page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Tg(MtTPRMET)243Lng expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  MET (4233)

  Met	(MGI:96969)

• Mutation details: The transgene contains a mouse metallothionein 1 promoter and the human met proto-oncogene (hepatocyte growth factor receptor). Four founder lines were established (line 1 = 243 and line 2 = 773). (J:71573)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Tumor Data

List all tumor models in MMHCdb carrying Tg(MtTPRMET)243Lng

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:71573 Liang TJ, et al., Transgenic expression of tpr-met oncogene leads to development of mammary hyperplasia and tumors. J Clin Invest. 1996 Jun 15;97(12):2872-7
• All: 2 reference(s)