Tg(Crh)227.1Pbl
Transgene Detail

Summary

• Symbol: Tg(Crh)227.1Pbl
• Name: transgene insertion 227.1, Wylie W Vale
• MGI ID: MGI:3055440
• Synonyms: CRF-OE, CRF Tg, CRH-th, Tg(CRF)227.1Pbl, Tg(Crh)
• Transgene: Tg(Crh)227.1Pbl Location: unknown
• Alliance: Tg(Crh)227.1Pbl page

Transgene origin

• Strain of Origin: C57BL/6 x SJL

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Crh)227.1Pbl expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  rat

  Crh (81648)

  Crh	(MGI:88496)

• Mutation details: The transgene contains the rat corticotropin releasing hormone (Crh) coding region driven by the murine metallothionine 1 promoter (Mt1). (J:92996)

Disease models

Expression

In Structures Affected by this Mutation:

8 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:92996 Stenzel-Poore MP, et al., Development of Cushing's syndrome in corticotropin-releasing factor transgenic mice. Endocrinology. 1992 Jun;130(6):3378-86
• All: 22 reference(s)