Tg(IRS1)1Mhep
Transgene Detail

Summary

• Symbol: Tg(IRS1)1Mhep
• Name: transgene insertion 1, Rolf Carlson
• MGI ID: MGI:3056765
• Transgene: Tg(IRS1)1Mhep Location: unknown
• Alliance: Tg(IRS1)1Mhep page

Transgene origin

• Strain of Origin: FVB

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Tg(IRS1)1Mhep expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  IRS1 (3667)

  Irs1	(MGI:99454)

• Mutation details: The transgene contains the human insulin receptor substrate 1 (IRS1) gene. Mice overexpress human IRS1 in the liver. (J:92999)

Disease models

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:92999 Tanaka S, et al., Biological effects of human insulin receptor substrate-1 overexpression in hepatocytes. Hepatology. 1997 Sep;26(3):598-604
• All: 3 reference(s)