Tg(Cebpb-tTA)5Bjd
Transgene Detail

Summary

• Symbol: Tg(Cebpb-tTA)5Bjd
• Name: transgene insertion 5, Hermann Bujard
• MGI ID: MGI:3056818
• Synonyms: g(tTALap)5Bjd, LAP-tTA, Tg(tTALap)5Uh
• Transgene: Tg(Cebpb-tTA)5Bjd Location: unknown
• Alliance: Tg(Cebpb-tTA)5Bjd page

Transgene origin

• Strain of Origin: NMRI

Transgene description

• Transgene Type: Transgenic (Transactivator)
• Mutation: Insertion
• Mutation details: This transgene contains the gene encoding the tetracycline regulated transactivator protein (tTA) driven by the rat Cebpb promoter (previously called liver-enriched activator protein). (J:93000)

Disease models

Tumor Data

List all tumor models in MMHCdb carrying Tg(Cebpb-tTA)5Bjd

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 3 strains available Cell Lines: 0 lines available

Notes

Transgenic mice on a C57BL/6J background are viable and fertile, and express tTA in the liver.

References

• Original: J:93000 Kistner A, et al., Doxycycline-mediated quantitative and tissue-specific control of gene expression in transgenic mice. Proc Natl Acad Sci U S A. 1996 Oct 1;93(20):10933-8
• All: 61 reference(s)