Dp(16Cbr1-Fam3b)1Rhr Cytogenetic Marker Detail

Summary

• Symbol
  Dp(16Cbr1-Fam3b)1Rhr
• Name
  duplication, Chr 16, R H Reeves 1
• Synonyms
  Dp(16Cbr1-ORF9)1Rhr, Is(16Cbr1-ORF9)1Rhr, Is(16Mx2-Cbr1)1Rhr, Is(16Mx2-Cbrl)1Rhr, Ts(16¹⁶)1Rhr

• Feature Type
  chromosomal duplication
• IDs
  MGI:3487250

Location &
Maps

• Sequence Map
  Chr16:93404725-97306136 bp

  From MGI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 16, Syntenic
• Mapping Data
  1 experiment

Human Diseases

• Mutations/Alleles
  1 with disease annotations

• References
  3 with disease annotations

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  38 phenotypes from multigenic genotypes
  31 phenotype references
  

• All Mutations and Alleles
  1
• Targeted
  1
• Find Mice (IMSR)
  1 strains or lines available

References

• Summaries
  All 32

  Diseases 3

  Phenotypes 31
• Earliest
  J:93223 Olson LE, et al., A chromosome 21 critical region does not cause specific down syndrome phenotypes. Science. 2004 Oct 22;306(5696):687-90
• Latest
  J:345472 Lana-Elola E, et al., Increased dosage of DYRK1A leads to congenital heart defects in a mouse model of Down syndrome. Sci Transl Med. 2024 Jan 24;16(731):eadd6883