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repro2 Gene Detail
Summary
  • Symbol
    repro2
  • Name
    reproductive mutant 2, JAX Reproductive Mutagenesis Program
  • Synonyms
    G1-374-15
  • Feature Type
    heritable phenotypic marker
  • IDs
    MGI:3512773
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr5:119945037-123550137 bp
    From MGI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, Syntenic
  • Mapping Data
    1 experiment
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotypes from 1 allele in 1 genetic background
    2 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygotes for this ENU-induced mutation exhibit reproductive defects such as male infertility, various sperm abnormalities including low sperm counts, and impaired fertilization.
References
more
  • Summaries
    All 2
    Phenotypes 2
  • Earliest
    J:117563 Lessard C, et al., Mutagenesis-generated mouse models of human infertility with abnormal sperm. Hum Reprod. 2007 Jan;22(1):159-66
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory