inad Gene Detail

Summary

• Symbol
  inad
• Name
  infantile neuroaxonal dystrophy

• Feature Type
  heritable phenotypic marker
• IDs
  MGI:3577064
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome 1, Syntenic
• Mapping Data
  1 experiment

Human Diseases

• Diseases
  1 with inad mouse models

Human Disease

Mouse Models

neurodegeneration with brain iron accumulation 2a

IDs

neurodegeneration with brain iron accumulation 2a      

DOID:0110735
ICD10CM:G23.0
OMIM:256600

View 1 model

Mouse Models

Human Disease Modeled: neurodegeneration with brain iron accumulation 2a

Allelic Composition	Genetic Background	Reference	Phenotypes
inad/inad	C57BL/6-inad	J:97670	View

Click on a disease name to see all genes associated with that disease.

• Mutations/Alleles
  1 with disease annotations

• References
  1 with disease annotations

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  13 phenotypes from 1 allele in 1 genetic background
  2 images
  1 phenotype reference
  

• All Mutations and Alleles
  1
• Spontaneous
  1
• Find Mice (IMSR)
  1 strains or lines available

Homozygous mutant mice die before sexual maturity and exhibit axonal dystrophic change appearing as spheroid bodies in the nervous system. Mice show progressive motor paralysis and atrophy of the hindlimbs.

References

• Summaries
  All 1

  Diseases 1

  Phenotypes 1
• Earliest
  J:97670 Matsushima Y, et al., A new mouse model for infantile neuroaxonal dystrophy, inad mouse, maps to mouse chromosome 1. Mamm Genome. 2005 Feb;16(2):73-8