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Spink10 Gene Detail
Summary
  • Symbol
    Spink10
  • Name
    serine peptidase inhibitor, Kazal type 10
  • Synonyms
    A230091H23Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:3584533
    NCBI Gene: 328971
  • Alliance
    gene page
  • Transcription Start Sites
    9 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:62681982-62797412 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 18, 35.22 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    3720 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3584533
 protein coding gene Chr18:62681982-62801141 (+)
129S1/SvImJ MGP_129S1SvImJ_G0024494
 protein coding gene Chr18:62580516-62597869 (+)
A/J MGP_AJ_G0024461
 protein coding gene Chr18:59913796-59928816 (+)
AKR/J MGP_AKRJ_G0024431
 protein coding gene Chr18:61562262-61579266 (+)
BALB/cJ MGP_BALBcJ_G0024460
 protein coding gene Chr18:60034493-60049081 (+)
C3H/HeJ MGP_C3HHeJ_G0024228
 protein coding gene Chr18:61799832-61817630 (+)
C57BL/6NJ MGP_C57BL6NJ_G0024907
 protein coding gene Chr18:64281785-64300004 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022338
 protein coding gene Chr18:59431023-59448249 (+)
CAST/EiJ MGP_CASTEiJ_G0023701
 protein coding gene Chr18:61669488-61685392 (+)
CBA/J MGP_CBAJ_G0024198
 protein coding gene Chr18:66357975-66378915 (+)
DBA/2J MGP_DBA2J_G0024328
 protein coding gene Chr18:59574234-59589557 (+)
FVB/NJ MGP_FVBNJ_G0024294
 protein coding gene Chr18:58968604-58983794 (+)
LP/J MGP_LPJ_G0024412
 protein coding gene Chr18:62469901-62484076 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0024323
 protein coding gene Chr18:67908360-67924083 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0024954
 protein coding gene Chr18:61764939-61779910 (+)
PWK/PhJ MGP_PWKPhJ_G0023444
 protein coding gene Chr18:59808178-59823208 (+)
SPRET/EiJ MGP_SPRETEiJ_G0023250
 protein coding gene Chr18:61990644-62006266 (+)
WSB/EiJ MGP_WSBEiJ_G0023765
 protein coding gene Chr18:61621783-61636537 (+)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    8
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 328971 NCBI Gene Model | MGI Sequence Detail 115431 C57BL/6J ±  kb
transcript NM_177829 RefSeq | MGI Sequence Detail 1135 C57BL/6  
polypeptide Q8CAC8 UniProt | EBI | MGI Sequence Detail 162 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 8
    cDNA 8

    Microarray probesets 4
References
more
  • Summaries
    All 26
    Gene Ontology 2
    Phenotypes 6
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory