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Cntnap3 Gene Detail
Summary
  • Symbol
    Cntnap3
  • Name
    contactin associated protein-like 3
  • Feature Type
    protein coding gene
  • IDs
    MGI:3588199
    NCBI Gene: 238680
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:64883996-65051769 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 33.46 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    4304 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3588199
 protein coding gene Chr13:64883994-65051845 (-)
129S1/SvImJ MGP_129S1SvImJ_G0020681
 protein coding gene Chr13:64764511-64928145 (-)
A/J MGP_AJ_G0020635
 protein coding gene Chr13:62411087-62568137 (-)
AKR/J MGP_AKRJ_G0020612
 protein coding gene Chr13:64476527-64641169 (-)
BALB/cJ MGP_BALBcJ_G0020633
 protein coding gene Chr13:62841039-62996329 (-)
C3H/HeJ MGP_C3HHeJ_G0020428
 protein coding gene Chr13:64016313-64173325 (-)
C57BL/6NJ MGP_C57BL6NJ_G0021069
 protein coding gene Chr13:66863886-67039643 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018645
 protein coding gene Chr13:60056966-60211578 (-)
CAST/EiJ MGP_CASTEiJ_G0019945
 protein coding gene Chr13:64018697-64189092 (-)
CBA/J MGP_CBAJ_G0020388
 protein coding gene Chr13:69434987-69611628 (-)
DBA/2J MGP_DBA2J_G0020513
 protein coding gene Chr13:62251783-62405040 (-)
FVB/NJ MGP_FVBNJ_G0020492
 protein coding gene Chr13:61344256-61495139 (-)
LP/J MGP_LPJ_G0020587
 protein coding gene Chr13:65059314-65221803 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0020521
 protein coding gene Chr13:68361389-68543700 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0021111
 protein coding gene Chr13:63807669-63964217 (-)
PWK/PhJ MGP_PWKPhJ_G0019699
 protein coding gene Chr13:61800515-61958409 (-)
SPRET/EiJ MGP_SPRETEiJ_G0019525
 protein coding gene Chr13:61973727-62150648 (-)
WSB/EiJ MGP_WSBEiJ_G0020005
 protein coding gene Chr13:64279367-64448243 (-)



Homology
more
  • Human Ortholog
    CNTNAP3, contactin associated protein family member 3
  • Vertebrate Orthologs
    5
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CNTNAP3, contactin associated protein family member 3
  • Synonyms
    CASPR3, CNTNAP3A
  • Links
    NCBI Gene ID: 79937
    neXtProt AC: NX_Q9BZ76
    UniProt: Q9BZ76

  • Chr Location
    9p12; chr9:39064710-39288315 (-)  GRCh38
  • Human Ortholog
    CNTNAP3B, contactin associated protein family member 3B
  • Links
    NCBI Gene ID: 728577
    neXtProt AC: NX_Q96NU0
    UniProt: Q96NU0

  • Chr Location
    9p11.2
  • Human Ortholog
    CNTNAP3C, contactin associated protein family member 3C
  • Links
    NCBI Gene ID: 100289279

  • Chr Location
    chr9:61330441-61461466 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit normal brain morphology but impaired motor learning.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    721
  • Tissues
    3
  • cDNA Data
    5
  • Literature Summary
    4
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000033063 Ensembl Gene Model | MGI Sequence Detail 167774 C57BL/6J ±  kb
transcript ENSMUST00000091554 Ensembl | MGI Sequence Detail 6344 Not Applicable  
polypeptide ENSMUSP00000089140 Ensembl | MGI Sequence Detail 1287 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR000421 Coagulation factor 5/8 C-terminal domain
    IPR013320 Concanavalin A-like lectin/glucanase domain superfamily
    IPR000742 EGF-like domain
    IPR002181 Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain
    IPR036056 Fibrinogen-like, C-terminal
    IPR008979 Galactose-binding-like domain superfamily
    IPR001791 Laminin G domain
    IPR050372 Neurexin-related cell adhesion and synaptic protein
  • GlyGen
    E9PY62 2 sites, 2 N-linked glycans (2 sites)
Molecular
Reagents
less
  • All nucleic 5
    cDNA 5

    Microarray probesets 6
References
more
  • Summaries
    All 26
    Developmental Gene Expression 4
    Gene Ontology 1
    Phenotypes 10
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory