About   Help   FAQ
Ccl26 Gene Detail
Summary
  • Symbol
    Ccl26
  • Name
    C-C motif chemokine ligand 26
  • Synonyms
    Ccl26l, eotaxin-3
  • Feature Type
    protein coding gene
  • IDs
    MGI:3589281
    NCBI Gene: 541307
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr5:135589302-135592423 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 75.27 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    243 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3589281
 protein coding gene Chr5:135589302-135592423 (-)
129S1/SvImJ MGP_129S1SvImJ_G0030184
 protein coding gene Chr5:140108319-140112940 (-)
A/J MGP_AJ_G0030152
 protein coding gene Chr5:134114633-134117436 (-)
AKR/J MGP_AKRJ_G0030085
 protein coding gene Chr5:138461617-138464589 (-)
BALB/cJ MGP_BALBcJ_G0030162
 protein coding gene Chr5:135452676-135455901 (-)
C3H/HeJ MGP_C3HHeJ_G0029878
 protein coding gene Chr5:139024832-139029460 (-)
C57BL/6NJ MGP_C57BL6NJ_G0030615
 protein coding gene Chr5:145331833-145339356 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027838
 protein coding gene Chr5:128398568-128401546 (-)
CAST/EiJ MGP_CASTEiJ_G0029287
 protein coding gene Chr5:138435289-138438165 (-)
CBA/J MGP_CBAJ_G0029848
 protein coding gene Chr5:151020719-151023575 (-)
DBA/2J MGP_DBA2J_G0029999
 protein coding gene Chr5:134008252-134011055 (-)
FVB/NJ MGP_FVBNJ_G0029954
 protein coding gene Chr5:133147847-133150703 (-)
LP/J MGP_LPJ_G0030087
 protein coding gene Chr5:140551410-140556058 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0029986
 protein coding gene Chr5:154007817-154011756 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0030655
 protein coding gene Chr5:138217523-138221161 (-)
PWK/PhJ MGP_PWKPhJ_G0029002
 protein coding gene Chr5:133053111-133055912 (-)
SPRET/EiJ MGP_SPRETEiJ_G0028837
 protein coding gene Chr5:135769046-135771818 (-)
WSB/EiJ MGP_WSBEiJ_G0029361
 protein coding gene Chr5:138956613-138960387 (-)



Homology
more
  • Human Ortholog
    CCL26, C-C motif chemokine ligand 26
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CCL26, C-C motif chemokine ligand 26
  • Synonyms
    IMAC, MIP-4a, MIP-4alpha, SCYA26, TSC-1
  • Links
    NCBI Gene ID: 10344
    neXtProt AC: NX_Q9Y258
    UniProt: Q9Y258

  • Chr Location
    7q11.23; chr7:75769524-75791597 (-)  GRCh38
Human Diseases
more
  • Diseases
    3 with human CCL26 associations

Human Disease Mouse Models
      
IDs
IDs
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    21
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    733
  • Tissues
    19
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 541307 NCBI Gene Model | MGI Sequence Detail 3122 C57BL/6J ±  kb
transcript NM_001013412 RefSeq | MGI Sequence Detail 282 C57BL/6  
polypeptide NP_001013430 RefSeq | MGI Sequence Detail 93 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR039809 Chemokine beta/gamma/delta
    IPR001811 Chemokine interleukin-8-like domain
    IPR036048 Chemokine interleukin-8-like superfamily
Molecular
Reagents
less

  • Microarray probesets 1
References
more
  • Summaries
    All 20
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 9
  • Earliest
    J:98708 Pope SM, et al., Identification of a cooperative mechanism involving interleukin-13 and eotaxin-2 in experimental allergic lung inflammation. J Biol Chem. 2005 Apr 8;280(14):13952-61
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory