About   Help   FAQ
repro3 Gene Detail
Summary
  • Symbol
    repro3
  • Name
    reproductive mutation 3, JAX Reproductive Mutagenesis Program
  • Synonyms
    G1-397-28
  • Feature Type
    heritable phenotypic marker
  • IDs
    MGI:3590178
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr10:44021933-46720483 bp
    From MGI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, Syntenic
  • Mapping Data
    1 experiment
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotypes from 1 allele in 1 genetic background
    1 phenotype reference
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygotes for this ENU-induced mutation exhibit male reproductive abnormalities including infertility, low sperm concentration, abnormal sperm head and tail morphology, no sperm motility, and inability of sperm to fertilize oocytes.
References
more
  • Summaries
    All 2
    Phenotypes 1
  • Earliest
    J:117563 Lessard C, et al., Mutagenesis-generated mouse models of human infertility with abnormal sperm. Hum Reprod. 2007 Jan;22(1):159-66
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory