Tg(PDGFB-MAPT*V337M)1Atak
Transgene Detail

Summary

• Symbol: Tg(PDGFB-MAPT*V337M)1Atak
• Name: transgene insertion 1, Akihiko Takashima
• MGI ID: MGI:3604147
• Synonyms: V337M Tg
• Transgene: Tg(PDGFB-MAPT*V337M)1Atak Location: unknown
• Alliance: Tg(PDGFB-MAPT*V337M)1Atak page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Tg(PDGFB-MAPT*V337M)1Atak expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  MAPT (4137)

  Mapt	(MGI:97180)

• Mutation details: Expression of human microtubule-associated protein tau with a V337M substitution was driven by the platelet derived growth factor, B polypeptide promoter. Expression was observed in the cell bodies and proximal dendrites of hippocampal neurons. (J:100964)

Disease models

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:100964 Tanemura K, et al., Neurodegeneration with tau accumulation in a transgenic mouse expressing V337M human tau. J Neurosci. 2002 Jan 1;22(1):133-41
• All: 4 reference(s)