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Rgs22 Gene Detail
Summary
  • Symbol
    Rgs22
  • Name
    regulator of G-protein signalling 22
  • Feature Type
    protein coding gene
  • IDs
    MGI:3613651
    NCBI Gene: 626596
  • Alliance
    gene page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:36009625-36140546 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 14.46 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    3292 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3613651
 protein coding gene Chr15:35960664-36140718 (-)
129S1/SvImJ MGP_129S1SvImJ_G0021789
 protein coding gene Chr15:34376573-34520055 (-)
A/J MGP_AJ_G0021750
 protein coding gene Chr15:33086444-33222186 (-)
AKR/J MGP_AKRJ_G0021728
 protein coding gene Chr15:33994581-34141808 (-)
BALB/cJ MGP_BALBcJ_G0021756
 protein coding gene Chr15:33089068-33227785 (-)
C3H/HeJ MGP_C3HHeJ_G0021531
 protein coding gene Chr15:33971472-34110585 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022195
 protein coding gene Chr15:35676210-35825592 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019733
 protein coding gene Chr15:30915398-31035300 (-)
CAST/EiJ MGP_CASTEiJ_G0021047
 protein coding gene Chr15:34365945-34514470 (-)
CBA/J MGP_CBAJ_G0021500
 protein coding gene Chr15:36824717-36982770 (-)
DBA/2J MGP_DBA2J_G0021624
 protein coding gene Chr15:32908187-33044145 (-)
FVB/NJ MGP_FVBNJ_G0021602
 protein coding gene Chr15:32304320-32444481 (-)
LP/J MGP_LPJ_G0021693
 protein coding gene Chr15:34289934-34422172 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0021627
 protein coding gene Chr15:39943314-40097657 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022218
 protein coding gene Chr15:34142390-34296585 (-)
PWK/PhJ MGP_PWKPhJ_G0020791
 protein coding gene Chr15:32923382-33062287 (-)
SPRET/EiJ MGP_SPRETEiJ_G0020629
 protein coding gene Chr15:33854582-33994856 (-)
WSB/EiJ MGP_WSBEiJ_G0021103
 protein coding gene Chr15:34124754-34263111 (-)



Homology
more
  • Human Ortholog
    RGS22, regulator of G protein signaling 22
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RGS22, regulator of G protein signaling 22
  • Synonyms
    CT145, PRTD-NY2
  • Links
    NCBI Gene ID: 26166
    neXtProt AC: NX_Q8NE09
    UniProt: Q8NE09

  • Chr Location
    8q22.2; chr8:99960936-100131268 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    18
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    713
  • Tissues
    7
  • cDNA Data
    2
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000037627 Ensembl Gene Model | MGI Sequence Detail 130922 C57BL/6J ±  kb
transcript ENSMUST00000172831 Ensembl | MGI Sequence Detail 4006 Not Applicable  
polypeptide ENSMUSP00000134259 Ensembl | MGI Sequence Detail 1258 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 2
    cDNA 2

    Microarray probesets 1
References
more
  • Summaries
    All 29
    Developmental Gene Expression 1
    Gene Ontology 6
    Phenotypes 11
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory