Mir133b MGI Mouse Gene Detail - MGI:3618720

Symbol

Mir133b
Name

microRNA 133b
Synonyms

mir 133b, Mirn133b, mmu-mir-133b

Feature Type

miRNA gene
IDs

MGI:3618720
NCBI Gene: 723817
Member of

Mirc37 cluster
Alliance

gene page
Transcription Start Sites

1 TSS

Sequence Map

Chr1:20752993-20753111 bp, + strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 1, 6.41 cM
Mapping Data

1 experiment

SNPs within 2kb

109 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_3618720	miRNA gene	Chr1:20752993-20753111 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0007597	miRNA gene	Chr1:18300310-18300428 (+)
A/J	MGP_AJ_G0007594	miRNA gene	Chr1:18082472-18082590 (+)
AKR/J	MGP_AKRJ_G0007566	miRNA gene	Chr1:18108754-18108872 (+)
BALB/cJ	MGP_BALBcJ_G0007568	miRNA gene	Chr1:17772107-17772225 (+)
C3H/HeJ	MGP_C3HHeJ_G0007515	miRNA gene	Chr1:18147553-18147671 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0007743	miRNA gene	Chr1:19170287-19170405 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0006921	miRNA gene	Chr1:16233958-16234076 (+)
CAST/EiJ	MGP_CASTEiJ_G0007415	miRNA gene	Chr1:18240056-18240174 (+)
CBA/J	MGP_CBAJ_G0007490	miRNA gene	Chr1:19602005-19602123 (+)
DBA/2J	MGP_DBA2J_G0007523	miRNA gene	Chr1:17582135-17582253 (+)
FVB/NJ	MGP_FVBNJ_G0007539	miRNA gene	Chr1:17348626-17348744 (+)
LP/J	MGP_LPJ_G0007605	miRNA gene	Chr1:18526209-18526327 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0007513	miRNA gene	Chr1:20557561-20557679 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0007744	miRNA gene	Chr1:18098169-18098287 (+)
PWK/PhJ	MGP_PWKPhJ_G0007348	miRNA gene	Chr1:17332105-17332223 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0007253	miRNA gene	Chr1:18193686-18193804 (+)
WSB/EiJ	MGP_WSBEiJ_G0007479	miRNA gene	Chr1:18026761-18026879 (+)

Human Ortholog

MIR133B, microRNA 133b

Vertebrate Orthologs

1

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

MIR133B, microRNA 133b
Synonyms

mir-133b, MIRN133B, miRNA133B
Links

HGNC:31759

NCBI Gene ID: 442890
Chr Location

chr6:52148923-52149041 (+) GRCh38

MGI Vertebrate Homology

Mir133b stringent orthology
1 human;1 mouse
HCOP

vertebrate homology predictions: MIR133B
Gene Tree

Mir133b

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Phenotype Summary

1 phenotype from 1 allele in 1 genetic background
5 phenotype references

All Mutations and Alleles

4
Targeted

4
Genomic Mutations

2 involving Mir133b
Find Mice (IMSR)

0 strains or lines available

Mice homozygous for a null mutation are viable and fertile with no gross abnormalities.

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All GO Annotations

7
GO References

4

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

760
Tissues

17
Literature Summary

17

Images

Tissue x Stage Matrix

Other Mouse Links

GEO

Expression Atlas

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All Sequences

23
RefSeq

1

Ensembl

ENSMUSG00000065480 (Evidence)
NCBI Gene

723817

Representative Sequences				Length	Strain/Species	Flank
	genomic	723817	NCBI Gene Model \| MGI Sequence Detail	119	C57BL/6J	± kb
	transcript	NR_029902	RefSeq \| MGI Sequence Detail	119	C57BL/6

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All nucleic 7

Primer pair 3

Other 4

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miRBase

MI0000821

Summaries

All 39

Developmental Gene Expression 17

Gene Ontology 4

Phenotypes 5
Earliest

J:105741 Griffiths-Jones S, et al., miRBase: microRNA sequences, targets and gene nomenclature. Nucleic Acids Res. 2006 Jan 1;34(Database issue):D140-4
Latest

J:328212 Klockner I, et al., Control of CRK-RAC1 activity by the miR-1/206/133 miRNA family is essential for neuromuscular junction function. Nat Commun. 2022 Jun 8;13(1):3180

TSS for Mir133b:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr6052	Chr1:20753079-20753081 (+)	87 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/05/2024 MGI 6.24