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Mir194-2 Gene Detail
Summary
  • Symbol
    Mir194-2
  • Name
    microRNA 194-2
  • Synonyms
    mir 194-2, Mirn194-2, mmu-mir-194-2
  • Feature Type
    miRNA gene
  • IDs
    MGI:3618738
    NCBI Gene: 723957
  • Member of
    Mirc17 cluster
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:6314673-6314758 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 19, 4.39 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    27 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3618738
miRNA gene Chr19:6314673-6314758 (+)
129S1/SvImJ MGP_129S1SvImJ_G0008416
miRNA gene Chr19:3310323-3310408 (+)
A/J MGP_AJ_G0008405
miRNA gene Chr19:3129435-3129520 (+)
AKR/J MGP_AKRJ_G0008390
miRNA gene Chr19:3222497-3222582 (+)
BALB/cJ MGP_BALBcJ_G0008391
miRNA gene Chr19:3125308-3125393 (+)
C3H/HeJ MGP_C3HHeJ_G0008335
miRNA gene Chr19:3242284-3242369 (+)
C57BL/6NJ MGP_C57BL6NJ_G0008592
miRNA gene Chr19:3367949-3368034 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0007619
miRNA gene Chr19:3050337-3050422 (+)
CAST/EiJ MGP_CASTEiJ_G0008195
miRNA gene Chr19:3265631-3265716 (+)
CBA/J MGP_CBAJ_G0008300
miRNA gene Chr19:3536872-3536957 (+)
DBA/2J MGP_DBA2J_G0008334
miRNA gene Chr19:3118420-3118505 (+)
FVB/NJ MGP_FVBNJ_G0008356
miRNA gene Chr19:3131851-3131936 (+)
LP/J MGP_LPJ_G0008419
miRNA gene Chr19:3279243-3279328 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0008321
miRNA gene Chr19:3341597-3341682 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0008581
miRNA gene Chr19:3250310-3250395 (+)
PWK/PhJ MGP_PWKPhJ_G0008119
miRNA gene Chr19:3147574-3147659 (+)
SPRET/EiJ MGP_SPRETEiJ_G0007995
miRNA gene Chr19:3209642-3209727 (+)
WSB/EiJ MGP_WSBEiJ_G0008278
miRNA gene Chr19:3262050-3262135 (+)



Homology
more
  • Human Ortholog
    MIR194-2, microRNA 194-2
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MIR194-2, microRNA 194-2
  • Synonyms
    mir-194-2, MIRN194-2
  • Links
    NCBI Gene ID: 406970

  • Chr Location
    chr11:64891355-64891439 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    3 phenotype references
Mice homozygous for a targeted deletion are viable with no observed pathologies.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • Literature Summary
Sequences &
Gene Models
less
  • All Sequences
  • RefSeq
Representative SequencesLengthStrain/SpeciesFlank
genomic 723957 NCBI Gene Model | MGI Sequence Detail 86 C57BL/6J ±  kb
transcript NR_029830 RefSeq | MGI Sequence Detail 86 C57BL/6  
For the selected sequence
Molecular
Reagents
less
  • All nucleic 7
    Primer pair 3
    Other 4
Other Database
Links
less
miRBase MI0000733
References
more
  • Summaries
    All 26
    Developmental Gene Expression 9
    Gene Ontology 5
    Phenotypes 3
  • Earliest
    J:105741 Griffiths-Jones S, et al., miRBase: microRNA sequences, targets and gene nomenclature. Nucleic Acids Res. 2006 Jan 1;34(Database issue):D140-4
  • Latest
    J:318874 Chang YM, et al., Loss of hepatic miR-194 promotes liver regeneration and protects from acetaminophen-induced acute liver injury. Biochem Pharmacol. 2022 Jan;195:114862

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory