Mir194-2 MGI Mouse Gene Detail - MGI:3618738

Symbol

Mir194-2
Name

microRNA 194-2
Synonyms

mir 194-2, Mirn194-2, mmu-mir-194-2

Feature Type

miRNA gene
IDs

MGI:3618738
NCBI Gene: 723957
Member of

Mirc17 cluster
Alliance

gene page
Transcription Start Sites

2 TSS

Sequence Map

Chr19:6314673-6314758 bp, + strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 19, 4.39 cM
Mapping Data

1 experiment

SNPs within 2kb

27 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_3618738	miRNA gene	Chr19:6314673-6314758 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0008416	miRNA gene	Chr19:3310323-3310408 (+)
A/J	MGP_AJ_G0008405	miRNA gene	Chr19:3129435-3129520 (+)
AKR/J	MGP_AKRJ_G0008390	miRNA gene	Chr19:3222497-3222582 (+)
BALB/cJ	MGP_BALBcJ_G0008391	miRNA gene	Chr19:3125308-3125393 (+)
C3H/HeJ	MGP_C3HHeJ_G0008335	miRNA gene	Chr19:3242284-3242369 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0008592	miRNA gene	Chr19:3367949-3368034 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0007619	miRNA gene	Chr19:3050337-3050422 (+)
CAST/EiJ	MGP_CASTEiJ_G0008195	miRNA gene	Chr19:3265631-3265716 (+)
CBA/J	MGP_CBAJ_G0008300	miRNA gene	Chr19:3536872-3536957 (+)
DBA/2J	MGP_DBA2J_G0008334	miRNA gene	Chr19:3118420-3118505 (+)
FVB/NJ	MGP_FVBNJ_G0008356	miRNA gene	Chr19:3131851-3131936 (+)
LP/J	MGP_LPJ_G0008419	miRNA gene	Chr19:3279243-3279328 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0008321	miRNA gene	Chr19:3341597-3341682 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0008581	miRNA gene	Chr19:3250310-3250395 (+)
PWK/PhJ	MGP_PWKPhJ_G0008119	miRNA gene	Chr19:3147574-3147659 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0007995	miRNA gene	Chr19:3209642-3209727 (+)
WSB/EiJ	MGP_WSBEiJ_G0008278	miRNA gene	Chr19:3262050-3262135 (+)

Human Ortholog

MIR194-2, microRNA 194-2

Vertebrate Orthologs

1

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

MIR194-2, microRNA 194-2
Synonyms

mir-194-2, MIRN194-2
Links

HGNC:31565

NCBI Gene ID: 406970
Chr Location

chr11:64891355-64891439 (-) GRCh38

MGI Vertebrate Homology

Mir194-2 stringent orthology
1 human;1 mouse
HCOP

vertebrate homology predictions: MIR194-2
Gene Tree

Mir194-2

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Phenotype Summary

1 phenotype from 1 allele in 1 genetic background
3 phenotype references

All Mutations and Alleles

2
Targeted

2
Find Mice (IMSR)

3 strains or lines available

Mice homozygous for a targeted deletion are viable with no observed pathologies.

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All GO Annotations

5
GO References

5

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

804
Tissues

51
Literature Summary

9

Images

Tissue x Stage Matrix

Other Mouse Links

GEO

Expression Atlas

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All Sequences

24
RefSeq

1

Ensembl

ENSMUSG00000065582 (Evidence)
NCBI Gene

723957

Representative Sequences				Length	Strain/Species	Flank
	genomic	723957	NCBI Gene Model \| MGI Sequence Detail	86	C57BL/6J	± kb
	transcript	NR_029830	RefSeq \| MGI Sequence Detail	86	C57BL/6

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All nucleic 7

Primer pair 3

Other 4

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miRBase

MI0000733

Summaries

All 26

Developmental Gene Expression 9

Gene Ontology 5

Phenotypes 3
Earliest

J:105741 Griffiths-Jones S, et al., miRBase: microRNA sequences, targets and gene nomenclature. Nucleic Acids Res. 2006 Jan 1;34(Database issue):D140-4
Latest

J:318874 Chang YM, et al., Loss of hepatic miR-194 promotes liver regeneration and protects from acetaminophen-induced acute liver injury. Biochem Pharmacol. 2022 Jan;195:114862

TSS for Mir194-2:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr154596	Chr19:6313291-6313313 (+)	-1,371 bp
Tssr154597	Chr19:6313635-6313662 (+)	-1,024 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24