Mir29b-2 MGI Mouse Gene Detail - MGI:3619047

Symbol

Mir29b-2
Name

microRNA 29b-2
Synonyms

mir 29b-2, Mirn29b-2, mmu-mir-29b-2

Feature Type

miRNA gene
IDs

MGI:3619047
NCBI Gene: 723963
Member of

Mirc29 cluster
Alliance

gene page
Transcription Start Sites

1 TSS

Sequence Map

Chr1:194719348-194719428 bp, + strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 1, 98.41 cM
Mapping Data

1 experiment

SNPs within 2kb

55 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_3619047	miRNA gene	Chr1:194719348-194719428 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0007696	miRNA gene	Chr1:202218565-202218645 (+)
A/J	MGP_AJ_G0007691	miRNA gene	Chr1:193915683-193915763 (+)
AKR/J	MGP_AKRJ_G0007664	miRNA gene	Chr1:199650689-199650769 (+)
BALB/cJ	MGP_BALBcJ_G0007667	miRNA gene	Chr1:194618918-194618998 (+)
C3H/HeJ	MGP_C3HHeJ_G0007613	miRNA gene	Chr1:200539454-200539534 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0007842	miRNA gene	Chr1:208587234-208587314 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0007004	miRNA gene	Chr1:185313765-185313845 (+)
CAST/EiJ	MGP_CASTEiJ_G0007511	miRNA gene	Chr1:200106729-200106809 (+)
CBA/J	MGP_CBAJ_G0007587	miRNA gene	Chr1:216282842-216282922 (+)
DBA/2J	MGP_DBA2J_G0007621	miRNA gene	Chr1:192643136-192643216 (+)
FVB/NJ	MGP_FVBNJ_G0007636	miRNA gene	Chr1:190722212-190722292 (+)
LP/J	MGP_LPJ_G0007700	miRNA gene	Chr1:203360037-203360117 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0007610	miRNA gene	Chr1:222930037-222930117 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0007843	miRNA gene	Chr1:199505931-199506011 (+)
PWK/PhJ	MGP_PWKPhJ_G0007444	miRNA gene	Chr1:191945763-191945843 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0007342	miRNA gene	Chr1:198548648-198548728 (+)
WSB/EiJ	MGP_WSBEiJ_G0007576	miRNA gene	Chr1:199781911-199781991 (+)

Human Ortholog

MIR29B2, microRNA 29b-2

Vertebrate Orthologs

1

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

MIR29B2, microRNA 29b-2
Synonyms

MIRN29B2
Links

HGNC:31620

NCBI Gene ID: 407025
Chr Location

chr1:207802443-207802523 (-) GRCh38

MGI Vertebrate Homology

Mir29b-2 stringent orthology
1 human;1 mouse
HCOP

vertebrate homology predictions: MIR29B2
Gene Tree

Mir29b-2

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Phenotype Summary

4 phenotype references

All Mutations and Alleles

4
Endonuclease-mediated

2
Targeted

1
Transgenic

1
Genomic Mutations

1 involving Mir29b-2
Find Mice (IMSR)

5 strains or lines available

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All GO Annotations

9
GO References

7

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

764
Tissues

28
Literature Summary

10

Images

Tissue x Stage Matrix

Other Mouse Links

GEO

Expression Atlas

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All Sequences

24
RefSeq

1

Ensembl

ENSMUSG00000065412 (Evidence)
NCBI Gene

723963

Representative Sequences				Length	Strain/Species	Flank
	genomic	723963	NCBI Gene Model \| MGI Sequence Detail	81	C57BL/6J	± kb
	transcript	NR_029809	RefSeq \| MGI Sequence Detail	81	C57BL/6

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All nucleic 5

Primer pair 2

Other 3

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miRBase

MI0000712

Summaries

All 48

Developmental Gene Expression 10

Gene Ontology 7

Phenotypes 4
Earliest

J:101078 Smirnova L, et al., Regulation of miRNA expression during neural cell specification. Eur J Neurosci. 2005 Mar;21(6):1469-77
Latest

J:344746 Wang Y, et al., MicroRNA-29b-3p promotes intestinal permeability in IBS-D via targeting TRAF3 to regulate the NF-kappaB-MLCK signaling pathway. PLoS One. 2023;18(7):e0287597

TSS for Mir29b-2:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr10863	Chr1:194719422-194719426 (+)	76 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24