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Mir10a Gene Detail
Summary
  • Symbol
    Mir10a
  • Name
    microRNA 10a
  • Synonyms
    MicroRNA-10a, mir 10a, miR-10a, Mirn10a, mmu-mir-10a
  • Feature Type
    miRNA gene
  • IDs
    MGI:3619064
    NCBI Gene: 723893
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr11:96207991-96208100 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 59.83 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    43 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3619064
 miRNA gene Chr11:96207991-96208100 (+)
129S1/SvImJ MGP_129S1SvImJ_G0007864
 miRNA gene Chr11:98630326-98630435 (+)
A/J MGP_AJ_G0007857
 miRNA gene Chr11:94601751-94601860 (+)
AKR/J MGP_AKRJ_G0007832
 miRNA gene Chr11:97527918-97528027 (+)
BALB/cJ MGP_BALBcJ_G0007836
 miRNA gene Chr11:95101449-95101558 (+)
C3H/HeJ MGP_C3HHeJ_G0007782
 miRNA gene Chr11:97659158-97659267 (+)
C57BL/6NJ MGP_C57BL6NJ_G0008015
 miRNA gene Chr11:101711428-101711537 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0007156
 miRNA gene Chr11:92088338-92088447 (+)
CAST/EiJ MGP_CASTEiJ_G0007676
 miRNA gene Chr11:98482804-98482913 (+)
CBA/J MGP_CBAJ_G0007753
 miRNA gene Chr11:105873222-105873331 (+)
DBA/2J MGP_DBA2J_G0007788
 miRNA gene Chr11:94169190-94169299 (+)
FVB/NJ MGP_FVBNJ_G0007807
 miRNA gene Chr11:93647930-93648039 (+)
LP/J MGP_LPJ_G0007866
 miRNA gene Chr11:99166366-99166475 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0007777
 miRNA gene Chr11:105868705-105868814 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0008011
 miRNA gene Chr11:97835382-97835491 (+)
PWK/PhJ MGP_PWKPhJ_G0007603
 miRNA gene Chr11:95120606-95120715 (+)
SPRET/EiJ MGP_SPRETEiJ_G0007498
 miRNA gene Chr11:97561914-97562023 (+)
WSB/EiJ MGP_WSBEiJ_G0007743
 miRNA gene Chr11:97721663-97721772 (+)



Homology
more
  • Human Ortholog
    MIR10A, microRNA 10a
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MIR10A, microRNA 10a
  • Synonyms
    hsa-mir-10a, mir-10a, MIRN10A, miRNA10A
  • Links
    NCBI Gene ID: 406902

  • Chr Location
    chr17:48579838-48579947 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 2 alleles in 2 genetic backgrounds
    2 phenotypes from multigenic genotypes
    1 images
    19 phenotype references
Mice homozygous for a targeted deletion are viable with no observed pathologies. Mice homozygous for a knock-out allele exhibit increased frequency with of high-grade dysplasia and higher incidence of tubule-villous adenomas in Apcmin heterozygotes.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    713
  • Tissues
    5
  • Literature Summary
    11
Sequences &
Gene Models
less
  • All Sequences
    23
  • RefSeq
    1
Representative SequencesLengthStrain/SpeciesFlank
genomic 723893 NCBI Gene Model | MGI Sequence Detail 110 C57BL/6J ±  kb
transcript NR_029784 RefSeq | MGI Sequence Detail 110 C57BL/6  
For the selected sequence
Molecular
Reagents
less
  • All nucleic 3
    Primer pair 1
    Other 2
Other Database
Links
less
miRBase MI0000685
References
more
  • Summaries
    All 47
    Developmental Gene Expression 11
    Gene Ontology 6
    Phenotypes 19
  • Earliest
    J:56548 Zheng B, et al., Engineering a mouse balancer chromosome. Nat Genet. 1999 Aug;22(4):375-8
  • Latest
    J:329266 Chen CH, et al., Transgenic human HOXB1-9 directs anterior-posterior axial skeleton pattern in Hoxb1-9 deficient mice. Differentiation. 2022 Sep-Oct;127:1-11
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory