Mir17 MGI Mouse Gene Detail - MGI:3619065

Symbol

Mir17
Name

microRNA 17
Synonyms

mir 17, Mirn17, mmu-mir-17

Feature Type

miRNA gene
IDs

MGI:3619065
NCBI Gene: 723905
Member of

Mirc1 cluster
Alliance

gene page
Transcription Start Sites

3 TSS

Sequence Map

Chr14:115281103-115281186 bp, + strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 14, 59.40 cM
Mapping Data

2 experiments

SNPs within 2kb

77 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_3619065	miRNA gene	Chr14:115281103-115281186 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0008151	miRNA gene	Chr14:112497978-112498061 (+)
A/J	MGP_AJ_G0008139	miRNA gene	Chr14:108246535-108246618 (+)
AKR/J	MGP_AKRJ_G0008118	miRNA gene	Chr14:111781665-111781748 (+)
BALB/cJ	MGP_BALBcJ_G0008122	miRNA gene	Chr14:108763495-108763578 (+)
C3H/HeJ	MGP_C3HHeJ_G0008065	miRNA gene	Chr14:111607856-111607939 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0008313	miRNA gene	Chr14:116827458-116827541 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0007396	miRNA gene	Chr14:104417894-104417977 (+)
CAST/EiJ	MGP_CASTEiJ_G0007940	miRNA gene	Chr14:109385662-109385745 (+)
CBA/J	MGP_CBAJ_G0008033	miRNA gene	Chr14:121366694-121366777 (+)
DBA/2J	MGP_DBA2J_G0008069	miRNA gene	Chr14:108168138-108168221 (+)
FVB/NJ	MGP_FVBNJ_G0008093	miRNA gene	Chr14:106513397-106513480 (+)
LP/J	MGP_LPJ_G0008149	miRNA gene	Chr14:113525403-113525486 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0008060	miRNA gene	Chr14:126244453-126244536 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0008308	miRNA gene	Chr14:111207582-111207665 (+)
PWK/PhJ	MGP_PWKPhJ_G0007862	miRNA gene	Chr14:105114118-105114201 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0007757	miRNA gene	Chr14:107345170-107345253 (+)
WSB/EiJ	MGP_WSBEiJ_G0008018	miRNA gene	Chr14:111951906-111951989 (+)

Human Ortholog

MIR17, microRNA 17

Vertebrate Orthologs

2

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

MIR17, microRNA 17
Synonyms

hsa-mir-17, miR-17, miR17-3p, MIR17-5p, MIR91, MIRN17, MIRN91, miRNA17, miRNA91
Links

HGNC:31547

NCBI Gene ID: 406952
Chr Location

chr13:91350605-91350688 (+) GRCh38

MGI Vertebrate Homology

Mir17 stringent orthology
1 human;1 mouse;1 zebrafish
HCOP

vertebrate homology predictions: MIR17
Gene Tree

Mir17

less

Phenotype Summary

5 phenotype references

All Mutations and Alleles

5
Chemically induced (other)

1
Radiation induced

1
Targeted

3
Genomic Mutations

5 involving Mir17
Find Mice (IMSR)

1 strains or lines available

less

All GO Annotations

60
GO References

9

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

less

Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

921
Tissues

89
Literature Summary

42

Images

Tissue x Stage Matrix

Other Mouse Links

GEO

Expression Atlas

less

All Sequences

23
RefSeq

1

Ensembl

ENSMUSG00000065508 (Evidence)
NCBI Gene

723905

Representative Sequences				Length	Strain/Species	Flank
	genomic	723905	NCBI Gene Model \| MGI Sequence Detail	84	C57BL/6J	± kb
	transcript	NR_029785	RefSeq \| MGI Sequence Detail	84	C57BL/6

less

All nucleic 22

Primer pair 11

Other 11

less

miRBase

MI0000687

Summaries

All 95

Developmental Gene Expression 42

Gene Ontology 9

Phenotypes 5
Earliest

J:67314 Roix J, et al., Molecular and functional mapping of the piebald deletion complex on mouse chromosome 14. Genetics. 2001 Feb;157(2):803-15
Latest

J:339612 Altounian M, et al., Neuronal miR-17-5p contributes to interhemispheric cortical connectivity defects induced by prenatal alcohol exposure. Cell Rep. 2023 Aug 22;42(9):113020

TSS for Mir17:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr127128	Chr14:115279707-115279719 (+)	-1,390 bp
Tssr127129	Chr14:115280184-115280188 (+)	-917 bp
Tssr127130	Chr14:115280915-115280919 (+)	-186 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24