About   Help   FAQ
Mir34b Gene Detail
Summary
  • Symbol
    Mir34b
  • Name
    microRNA 34b
  • Synonyms
    mir 34b, Mirn34b, mmu-mir-34b
  • Feature Type
    miRNA gene
  • IDs
    MGI:3619364
    NCBI Gene: 723849
  • Member of
    Mirc21 cluster
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:51014862-51014945 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 27.83 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    69 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3619364
 miRNA gene Chr9:51014862-51014945 (-)
129S1/SvImJ MGP_129S1SvImJ_G0009203
 miRNA gene Chr9:50018932-50019015 (-)
A/J MGP_AJ_G0009184
 miRNA gene Chr9:48499056-48499139 (-)
AKR/J MGP_AKRJ_G0009173
 miRNA gene Chr9:49510795-49510878 (-)
BALB/cJ MGP_BALBcJ_G0009169
 miRNA gene Chr9:48249072-48249155 (-)
C3H/HeJ MGP_C3HHeJ_G0009109
 miRNA gene Chr9:50005082-50005165 (-)
C57BL/6NJ MGP_C57BL6NJ_G0009411
 miRNA gene Chr9:51417784-51417867 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0008268
 miRNA gene Chr9:47957438-47957521 (-)
CAST/EiJ MGP_CASTEiJ_G0008941
 miRNA gene Chr9:49944287-49944370 (-)
CBA/J MGP_CBAJ_G0009076
 miRNA gene Chr9:53239776-53239859 (-)
DBA/2J MGP_DBA2J_G0009107
 miRNA gene Chr9:48356538-48356621 (-)
FVB/NJ MGP_FVBNJ_G0009124
 miRNA gene Chr9:47572524-47572910 (-)
LP/J MGP_LPJ_G0009201
 miRNA gene Chr9:50386338-50386421 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0009090
 miRNA gene Chr9:54815624-54815707 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0009380
 miRNA gene Chr9:49499279-49499362 (-)
PWK/PhJ MGP_PWKPhJ_G0008866
 miRNA gene Chr9:48331089-48331172 (-)
SPRET/EiJ MGP_SPRETEiJ_G0008706
 miRNA gene Chr9:49796340-49796423 (-)
WSB/EiJ MGP_WSBEiJ_G0009036
 miRNA gene Chr9:49509543-49509626 (-)



Homology
more
  • Human Ortholog
    MIR34B, microRNA 34b
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MIR34B, microRNA 34b
  • Synonyms
    mir-34b, MIRN34B, miRNA34B
  • Links
    NCBI Gene ID: 407041

  • Chr Location
    chr11:111512938-111513021 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
Mice homozygous for a knock-out allele of Mir34b and Mir34c exhibit increased reprogramming efficiency of mouse embryonic fibroblasts.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    27
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    994
  • Tissues
    31
  • Literature Summary
    12
Sequences &
Gene Models
less
  • All Sequences
    23
  • RefSeq
    1
Representative SequencesLengthStrain/SpeciesFlank
genomic 723849 NCBI Gene Model | MGI Sequence Detail 84 C57BL/6J ±  kb
transcript NR_029655 RefSeq | MGI Sequence Detail 84 C57BL/6  
For the selected sequence
Molecular
Reagents
less
  • All nucleic 6
    Primer pair 2
    Other 4
Other Database
Links
less
miRBase MI0000404
References
more
  • Summaries
    All 34
    Developmental Gene Expression 12
    Gene Ontology 4
  • Earliest
    J:105741 Griffiths-Jones S, et al., miRBase: microRNA sequences, targets and gene nomenclature. Nucleic Acids Res. 2006 Jan 1;34(Database issue):D140-4
  • Latest
    J:326951 Wildung M, et al., miR449 Protects Airway Regeneration by Controlling AURKA/HDAC6-Mediated Ciliary Disassembly. Int J Mol Sci. 2022 Jul 13;23(14)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory