About   Help   FAQ
Mir379 Gene Detail
Summary
  • Symbol
    Mir379
  • Name
    microRNA 379
  • Synonyms
    mir 379, Mirn379, mmu-mir-379
Location &
Maps
more
  • Sequence Map
    Chr12:109675494-109675559 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 12, 60.56 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    49 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3619386
 miRNA gene Chr12:109675494-109675559 (+)
129S1/SvImJ ENSMUSG00200026334
 miRNA gene Chr12:101449259-101449324 (+)
A/J ENSMUSG00195045750
 miRNA gene Chr12:103981167-103981232 (+)
AKR/J ENSMUSG00220040698
 miRNA gene Chr12:101863454-101863519 (+)
BALB/cJ ENSMUSG00180051380
 miRNA gene Chr12:103212417-103212482 (+)
C3H/HeJ ENSMUSG00175050054
 miRNA gene Chr12:105791402-105791467 (+)
C57BL/6NJ ENSMUSG00215048075
 miRNA gene Chr12:102485359-102485424 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0007260
 miRNA gene Chr12:104154962-104155027 (+)
CAST/EiJ ENSTCUG00005019878
 miRNA gene Chr12:101963710-101963775 (+)
CBA/J ENSMUSG00210031700
 miRNA gene Chr12:102852860-102852925 (+)
DBA/2J ENSMUSG00185033951
 miRNA gene Chr12:104671398-104671463 (+)
FVB/NJ ENSMUSG00205039636
 miRNA gene Chr12:101897271-101897336 (+)
JF1/MsJ ENSUMUG00000036413
 miRNA gene Chr12:109429605-109429670 (+)
LP/J ENSMUSG00230032279
 miRNA gene Chr12:111714141-111714206 (+)
NOD/ShiLtJ ENSMUSG00190035516
 miRNA gene Chr12:83325750-83325815 (-)
NZO/HlLtJ ENSMUSG00225039803
 miRNA gene Chr12:113473019-113473084 (+)
PWK/PhJ ENSLUMG00010050120
 miRNA gene Chr12:102902112-102902177 (+)
SPRET/EiJ ENSMSPG00010018413
 miRNA gene Chr12:105185094-105185159 (+)
WSB/EiJ ENSIUOG00005009974
 miRNA gene Chr12:101894672-101894737 (+)



Homology
more
  • Human Ortholog
    MIR379, microRNA 379
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MIR379, microRNA 379
  • Synonyms
    hsa-mir-379, mir-379, MIRN379
  • Links
    NCBI Gene ID: 494328

  • Chr Location
    chr14:101022066-101022132 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
While males show normal incidence of streptozotocin-induced insulin-dependent diabetes, they are protected from key features of diabetic kidney disease, including renal dysfunction, glomerular expansion, renal fibrosis, and glomerular basement membrane thickening compared to diabetic wild-type mice.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    601
  • Tissues
    1
  • Literature Summary
    7
Sequences &
Gene Models
less
  • All Sequences
    24
  • RefSeq
    1
Representative SequencesLengthStrain/SpeciesFlank
genomic 723858 NCBI Gene Model | MGI Sequence Detail 66 C57BL/6J ±  kb
transcript NR_029880 RefSeq | MGI Sequence Detail 66 C57BL/6  
For the selected sequence
Molecular
Reagents
less
  • All nucleic 2
    Primer pair 1
    Other 1
Other Database
Links
less
miRBase MI0000796
References
more
  • Summaries
    All 38
    Developmental Gene Expression 7
    Gene Ontology 7
    Phenotypes 13
  • Earliest
    J:94160 Poy MN, et al., A pancreatic islet-specific microRNA regulates insulin secretion. Nature. 2004 Nov 11;432(7014):226-30
  • Latest
    J:360940 Narayanan R, et al., miRNA-mediated inhibition of an actomyosin network in hippocampal pyramidal neurons restricts sociability in adult male mice. Cell Rep. 2024 Jul 23;43(7):114429
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory